摘要
泽泻煎剂10.20g/kg抑制小鼠碳粒廓清速率及DNCB所致接触性皮炎;泽泻20g/kg明显减轻二甲苯引起的小鼠耳廓肿胀、抑制大鼠棉球肉芽组织增生,而对血清抗体含量及大鼠肾上腺内抗坏血酸含量无显著影响。
10 and 20g/kg ig of Rhizoma Alismatis (RA) markedly decrease the clearence rate of charcoal particles in mice, but have no significant effect on the weight of immune organs, or on the content of serum antibody hemolysin and immunoglobulin G and the delayed footpad edema induced by sheep red blood cell. The contact dermatitis of mouse pinnae immunized with dinitrochlorobenzene is inhibited by RA when it is given before challenge. In addition, RA 20g/kg suppresses the swelling of mouse pinnae induced by xylene and the proliferation of granuloma induced by cotton-pellet in rats. However, the content of vitamin C in the adrenal of rats is not clearly affected by RA.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1991年第10期622-625,共4页
China Journal of Chinese Materia Medica
关键词
泽泻
免疫系统
抗炎作用
Rhizoma Alismatis
immune system
anti-inflammatory activity
