摘要
目的:设计一种结构简单、操作方便的临床术中监护用肌松监测仪,为临床普及应用打好基础。方法:采用加速度传感器感应,输出人体的运动信息。将加速度传感器附着于待测量部位桡神经部位,加速度传感器反映待测量部位的肌肉松弛程度,通过加速度传感器输出单轴、双轴或三轴的加速度信息,再对该信息进行算法处理,以反映人体待测部位的肌松状态。以51单片机为核心控制单元,设计单次刺激(ST)、四成串刺激(TOF)以及强直刺激后计数(PTC)模式;完成肌松检测仪的设计后与临床常用的监测仪进行对比测试。结果:将设计完成的肌松监测仪与临床常用的监测仪进行对比测试,测试结果显示,肌松监测仪的ST、TOF及PTC的各项刺激参数测试指标均达到设计要求,ST频率为0.1~1 Hz可调,脉宽0.3μs;TOF频率为2 Hz,间隔为0.5 s;PTC频率为50 Hz、刺激持续时间为5 s;刺激电流0~60 mA。结论:所设计的肌松监测仪可作为临床监护时对患者肌肉松池的监测设备,其操作简便,体积小,便于普及。
Objective： To design a novel muscular relaxation monitoring system with simple construction, convenient operation and popularization which was used in monitoring of clinical operation so as to provide good basis for clinical popularization and application. Methods： The acceleration sensor was used to induce and output the motion information of the human body. When the acceleration sensor was attached to the musculospiral nerve at the measured site, and the acceleration sensor could reflect the muscular relaxation degree of the position which be measured. And then the acceleration sensor was used to output the acceleration information of the single axis, dual axis or three axis, and these information were further processed with algorithm so as to reflect the muscular relaxation state of the site was measured. The 51 single chip microcomputer was applied as the core control unit to design the single twitch（ST）, Train of Four（TOF） stimulation and post tetanic count（PTC） stimulation module. After the design of muscular relaxation monitoring system was completed, a comparison examination between it and clinically common monitoring was implemented. Results： The comparison results indicated that the test index of each stimulus parameter of ST, TOF and PTC could achieve requirement of design. And the frequency of ST was 0.1-1 Hz（adjustable）, and its pulse width was 0.3μs. And the frequency of TOF was 2 Hz, and the interval time was 0.5 s. And the frequency of PTC was 50 Hz, and the duration time of stimulus was 5 s. Besides, the current of stimulus was 0-60 m A. Conclusion： The designed system can be used as the monitoring experiment for muscle relaxation of patients in clinical monitoring. It has some advantages included easy operation, small volume and convenient popularization.
作者
崔红岩
徐圣普
冯莉
谢小波
CUI Hong-yan;XU Sheng-pu;FENG Li(Nerve Engineering Laboratory,Institute for Biomedical Engineering of Chinese Academy of Medical Sciences,Tianjin 300192,China.)
出处
《中国医学装备》
2018年第8期1-4,共4页
China Medical Equipment
基金
中国医学科学院医学与健康科技创新工程重大协同创新项目(2016-I2M-2-006)"人类疾病动物模型平台"
