摘要
目的观察小剂量阿司匹林对宫腔镜下宫腔粘连分离术(TCRA)后患者的影响。方法将中重度宫腔粘连患者51例,分为研究组30例与对照组21例。两组均行宫腔镜下TCRA术,术后均给予常规人工周期治疗,研究组在常规治疗的基础上给予小剂量阿司匹林口服,两组疗程均为3个月。比较两组患者治疗前后子宫内膜厚度、子宫内膜下动脉血流阻力指数、动脉搏动指数及疗效。结果治疗后,研究组患者子宫内膜下动脉血流阻力指数、动脉搏动指数均小于对照组,子宫内膜厚度厚于对照组,中重度粘连比例低于对照组(均P<0.05)。结论宫腔镜下TCRA术后行人工周期联合小剂量阿司匹林治疗,可降低宫腔粘连患者子宫内膜下动脉搏动指数和阻力指数,促进宫腔形态恢复。
Objective To observe the efficacy of low-dose aspirin for patients undergoing hysteroscopic transcervical resection of adhesion（TCRA）. Methods Fifty-one patients with moderate-severe intrauterine adhesion were divided into study group（30 cases） and control group（21 cases）.Both groups underwent hysteroscopic TCRA and then received conventional therapy of artificial menstrual cycle,the study group was given low-dose oral aspirin on the basis of conventional therapy after surgery,and the course of treatment was defined as 3 months in both groups.The endometrium thickness,endometrial arterial resistance index and arterial pulsatility index before and after treatment as well as efficacy were compared between the two groups. Results After treatment,the study group obtained lower endometrial arterial resistance index and arterial pulsatility index,greater endometrium thickness,and lower proportion of moderate-severe intrauterine adhesion compared to the control group（all P 〈0.05）. Conclusion Artificial menstrual cycle therapy combined with low-dose aspirin can reduce endometrial arterial pulsatility index and resistance index and promote uterine cavity recovery in the treatment of intrauterine adhesion patients undergoing hysteroscopic TCRA.
作者
明芳
李文怡
杨俊
M;LI Wen-yi;YANG Jun(The 1st Ward,Department of Gynecology,Liuzhou General Hospital,545006,China)
出处
《广西医学》
CAS
2018年第11期1221-1223,共3页
Guangxi Medical Journal
基金
广西医药卫生科研课题(Z2016116)
关键词
宫腔粘连
宫腔镜粘连分离术
阿司匹林
人工周期
疗效
Intrauterine Adhesion
Transcervical resection of adhesion
Aspirin
Artificial menstrual cycle
Efficacy
