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体位及药物综合干预对食管ESD术后食管狭窄的影响 被引量:6

Effect of comprehensive interventions of position and medication on esophageal strictures after endoscopic submucosal dissection
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摘要 目的分析体位及药物综合干预对内镜下食管黏膜剥离术(ESD)后发生食管狭窄的影响。方法选取2011年1月—2016年1月进行食管ESD术的患者82例,随机分为4组,对照组、研究组1各20例,研究组2、研究组3各21例。对照组给予常规护理干预,研究组1在对照组的基础上给予体位干预,研究组2在对照组的基础上给予药物干预,研究组3在对照组的基础上给予体位干预联合药物干预。结果术后3个月胃镜检查示食管狭窄共15例,其中对照组6例,实验1组4例,实验2组3例,实验3组2例。在狭窄程度方面,研究组均以轻度为主,尤其是研究组1和研究组3,无中度和重度患者。在吞咽困难程度方面,研究组均未出现4级现象,主要为1级和2级。结论体位干预降低胃液反流及早期适量糖皮质激素使用等措施,对食管ESD术后食管狭窄并发症的预防有积极作用。 Objective To investigate the effect of comprehensive interventions of position and medication on esophageal strictures after endoscopic submucosal dissection. Methods Totally 80 patients undergoing endoscopic submucosal dissection between January,2011 and January 2016 were included and randomly divided into four groups: control group( n = 20,routine nursing),study group 1( n = 20,routine care and position intervention),study group 2( n = 21,routine care and medication intervention) and group 3( n = 21,routine care and comprehensive interventions). Results Postoperative histopathology showed esophageal strictures in 15 cases(6 cases in control group,4 cases in study group 1,3 cases in study group 2,2 cases in study group3).There was no case with moderate to severe extent of esophageal stenosis in study group 1 and study group 3. According to the Stooler's dysphagia score,9 cases were classified as grade 1-2 in three study groups. Conclusion The comprehensive interventions of position and medication can effectively prevent the esophageal strictures after endoscopic submucosal dissection.
作者 何莉云 沈玲凤 孙庆梅 徐岷 何亚龙 HE Liyun;SHEN Lingfeng;SUN Qingmei;XU Min;HE Yalong(Department of Gastroenterology,Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,212001)
出处 《中西医结合护理(中英文)》 2018年第6期32-34,共3页 Journal of Clinical Nursing in Practice
基金 江苏大学医学临床科技发展基金项目(JLY20120177)
关键词 体位 糖皮质激素 内镜黏膜下剥离术 食管狭窄 胃食管反流 position glucocorticoid endoscopic submucosal dissection esophageal stric-tures gastroesophageal reflux
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