摘要
目的探讨益生菌联合谷氨酰胺在腹泻型肠易激综合征治疗中的作用。方法随机抽取本院收治的腹泻型肠易激综合征患者90例,按照随机数字表法分为研究组(常规治疗+益生菌+谷氨酰胺,n=45)与对照组(常规治疗,n=45)。对比两组治疗效果及安全性。结果治疗后,两组患者的腹痛、腹泻、腹胀等症状评分均降低,且研究组症状评分低于对照组(P<0.05);研究组治疗总有效率高于对照组(P<0.05);研究组腹痛、腹泻、腹胀消失时间均短于对照组(P<0.05);两组不良反应总发生率对比,差异无统计学意义(P>0.05)。结论腹泻型肠易激综合征治疗中联合应用益生菌与谷氨酰胺的效果更为理想。
Objective To explore the effect of probiotics combined with glutamine in the treatment of diarrheal irritablebowel syndrome. Methods A total of 90 patients with diarrhoeal irritable bowel syndrome admitted in our hospital wererandomly selected and divided into study group （conventional treatment＋probiotics＋glutamine, n=45） and control group（conventional treatment, n=45） according to the randomized numerical table method. The efficacy and safety of the twogroups were compared. Results After treatment, the scores of abdominal pain, diarrhea and abdominal distension in the twogroups decreased, and those of the study group were lower than the control group（P〈0.05）. The total efficiency of the studygroup was higher than that of the control group （P〈0.05）. The duration of abdominal pain, diarrhea and abdominaldistension in the study group were shorter than those in the control group （P〈0.05）. There was no statistically significantdifference in total incidence of adverse reactions between the two groups （P〉0.05）. Conclusion The efficacy of probioticsand glutamine in the treatment of diarrheal irritable bowel syndrome is more ideal.
作者
寇少敏
杜侃劳
KOU Shao-min;DU Kan-lao(Gastroenterology Department;Neurology Department,the People＇s Hospital of Shangzhou District,Shangluo 726000,China)
出处
《临床医学研究与实践》
2018年第22期29-30,共2页
Clinical Research and Practice
