摘要
目的探讨机械通气治疗小儿急性呼吸衰竭的临床效果。方法随机选取2015年5月-2017年5月成都市妇女儿童医院收治的小儿急性呼吸衰竭患儿80例,依据机械通气治疗结果将这些患儿分为成功组(30例)和失败组(10例)两组,对两组患儿的呼吸机参数、不同时间点的血气分析结果、上机后并发症及合并症发生情况进行统计分析。结果成功组患儿的PIP、PEEP均显著低于失败组(P<0.05)。组内比较,两组患儿上机后2 h、1 d、2 d的PO_2、PCO_2、HCO_3^-、Sa O_2、p H均显著高于上机前(P<0.05);组间比较,上机前成功组患儿的HCO_3^-显著高于失败组(P<0.05),但两组患儿的PO_2、PCO_2、Sa O_2、p H之间的差异均不显著(P>0.05),上机后1 d成功组患儿的PO_2显著高于失败组(P<0.05),上机后2 h、1 d、2 d成功组患儿的HCO_3^-、Sa O_2均显著低于失败组(P<0.05)。成功组患儿的呼吸机相关性肺炎、肺出血、肺不张、过度通气、多脏器功能衰竭发生率均显著低于失败组(P<0.05)。结论机械通气治疗小儿急性呼吸衰竭的临床效果好,值得在临床推广应用。
Objective To explore the clinical effect of mechanical ventilation in treatment of children with acute respiratory failure. Methods From May 2015 to May 2017, 80 children with acute respiratory failure were randomly selected from Chengdu Women＇s ＆ Children＇s Central Hospital, then they were divided into success group （30 children） and failure group （ 10 children） according to the results of mechanical ventilation. The parameters of ventilator, the results of blood gas analysis at different time points, and complications of mechanical ventilation in the two groups were statistically analyzed. Results PIP and PEEP in success group were statistically significantly lower than those in failure group （P〈0. 05） . In the two groups, PO2, PCO2, HCO3^-, SaO2, and pH values at 2 hours, one and two days after mechanical ventilation were statistically significantly higher than those before mechanical ventilation （ P〈0. 05 ） . Before mechanical ventilation, HCO3^- in success group was statistically significantly higher than that in failure group （ P〈0. 05 ） , but there was no statistically significant difference in PO2, PCO2, SaO2, and pH value between the two groups （P〉0. 05） . At one day after mechanical ventilation, PO2 in success group was statistically significantly lower than that in failure group （P〈0.05） . At 2 hours, one and two days after mechanical ventilation, HCO3 and SaO2 in success group were statistically significantly lower than those in failure group （P〈0. 05） . The incidence rates of ventilator-associated pneumonia, pulmonary hemorrhage, pnlmonary atelectasis, hyperventilation, multiple organ failure in success group were statistically significantly lower than those in failure group （ P〈0. 05 ） . Conclusion The clinical effect of mechanical ventilation in treatment of children with acute respiratory failure is good, and it is worthy of clinical application and promotion.
作者
郑静
张国英
ZHENG Jing;ZHANG Guo-Ying.(Chengdu Women＇s ＆ Children＇s Central Hospital, Chengdu, Sichuan 610017, China)
出处
《中国妇幼保健》
CAS
2018年第13期2982-2984,共3页
Maternal and Child Health Care of China
关键词
机械通气
小儿急性呼吸衰竭
临床效果
Mechanical ventilation
Child with acute respiratory failure
Clinical effect
