摘要
目的研究1990和2015年中国心血管病(CVD)危险因素疾病负担状况。方法利用2015年全球疾病负担研究结果,分析1990和2015年中国CVD危险因素的死亡人数、伤残调整寿命年(DALY)和人群归因分值(PAF)等指标的变化情况。结果 2015年,中国339.8万CVD死亡和6319.5万DALY归因于代谢因素、环境因素和行为因素,占CVD总死亡人数和总DALY的88.7%;DALY排名前五位的危险因素为高血压、高盐饮食、吸烟、全谷摄入不足和高血清TC,分别造成4236.1万、3210.8万、1721.2万、1658.6万和1426.9万DALY,其死亡人数和PAF也都排在前五位。1990-2015年,代谢因素上升最快,其CVD死亡人数上升112.9%、DALY上升93.6%;23种危险因素仅室内空气污染的CVD疾病负担下降,其余均上升。各危险因素的CVD疾病负担男性普遍高于女性,15~49岁人群代谢因素的疾病负担和PAF增长较快。结论 CVD相关的代谢因素快速增长,危险因素分布存在性别和年龄差异,有关部门应采取适当措施控制CVD疾病负担的发展。
Objective To analyze the states for burden of cardiovascular disease（CVD） attributed to risk factors in Chi- na in 1990 and 2015. Methods Data were extracted from the results of 2015 Global Burden of Disease Study. We analyzed data of CVD mortality, disability-adjusted life year（DALY） attributed to risk factors, and its population attributable fraction （PAF）, in China in 1990 and 2015. Change rates for related indicators were calculated. Results 3 398 thousand deaths and 63 195 thou- sand DALYs were caused by metabolic factors, environmental factors, and behavior factors in 2015 in China, which accounted for 88.7% of all CVD deaths and DALYs in 2015 in China. The top 5 risk factors that caused most DALYs were high systolic blood pressure, diet high in sodium, smoking, diet low in whole grains and high total cholesterol, accounted for 42 361 thousand, 32 108 thousand, 17 212 thousand, 16 586 thousand and 14 269 thousand CVD DALYs respectively,deaths and PAFs caused by them al- so ranked in top five. From 1990 to 2015 ,burden of CVD attributed to metabolic factors increased fastest in all risk factor clus- ters, with a 112. 9% increase on deaths and a 93.6% increase on DALYs. Burden of CVD attributed to all risk factors have in- creased except household air pollution from solid fuels between 1990 and 2015. Between sexes, CVD burden attributed to most risk factors were higher in males. CVD burden attributed to metabolic risk factors and its PAF in age group 15 N49 years experi- enced a rapid ascending in 1990 and 2015. Conclusion CVD related metabolic factors have increased rapidly and differences in composition of risk factors were detected between genders and ages. The authorities should take adequate measures to control the burden of CVD.
作者
张干深
罗丽莎
崔芳芳
宇传华
俞思伟
Zhang Ganshen;Luo Lisha;Cui Fangfang(Department of Epidemiology and healthStatistics, School of health sciences, Wu- han University（ 430071 ）, Wuhan)
出处
《中国卫生统计》
CSCD
北大核心
2018年第3期375-379,共5页
Chinese Journal of Health Statistics
基金
国家自然科学基金(81773552
81273179)
国家自然科学基金国际(地区)合作与交流项目(71661167007)
关键词
心血管病
危险因素
疾病负担
死亡
伤残调整生命年
Cardiovascular disease （ CVD ）
Risk factors
Burden of disease
Death
Disability adjusted life year （ DA-LY）
