摘要
通过测定游泳前后38只SD鼠的血浆丙二醛(MDA),发现血浆脂质过氧化物(LpO)含量在运动后1小时显著增高,运动后16小时有下降趋势但仍在高浓度状态。在用还原型谷胱甘肽(GSH)+VE+VC治疗后血浆LPO上升值显著下降。上述结果提示:血浆MDA可作为训练中的监护指标,建议运动性疾病易患者可试用自由基清除剂防治。
In order to determine the alteration of plasma lipid peroxides (LpO) induced by exercise and the effectof free radical scavengers on the exercise-induced elevation of LPO, plasma malondialdehyde (MDA) level of38 S-D rats were measured after swimming exercise with and without administrating free radical scavengers.It was found that plasma MDA increased up to 13.325nmol/ml 1 hour after exercise (p<0.01), 12.279nmol/ml 16 hours after exercise (p<0.01), compared with the resting level. With admininstrating of gluta-thione, Vitamin E and C, plasma MDA (1 hour after exercise) was significantly lower (9.592nmol/ml) thanthat without taking any scavenger (p<0.05). The results of the study indicated that exercise-induced eleva-tion of LpO occured during 1 to 16 hours after exercise and such elevation could be inhibited by free ra-dical scavengers.
出处
《中国运动医学杂志》
CAS
CSCD
北大核心
1991年第2期79-80,113,共3页
Chinese Journal of Sports Medicine
关键词
剧烈运动
自由基
实验研究
free radical scavenger
free radical response
