摘要
目的探讨铋剂四联方案用于消化性溃疡中的疗效及对幽门螺杆菌的影响。方法将在本院接受治疗的82例消化性溃疡患者依据治疗方法分为两组,各41例。对照组采用庆大霉素联合雷尼替丁治疗,观察组为胶体果胶铋、奥美拉唑、阿莫西林联合克拉霉素治疗。观察两组疗效及幽门螺杆菌转阴率。结果观察组治疗总有效率显著高于对照组(P<0.05);观察组幽门螺杆菌转阴率显著高于对照组(P<0.05);两组不良反应发生率无明显差异(P>0.05)。结论消化性溃疡选择胶体果胶铋、奥美拉唑、阿莫西林联合克拉霉素治疗可进一步缓解症状,提高幽门螺杆菌根除效果,促使溃疡尽快愈合,临床治疗价值较高。
Objective To investigate the curative effect of bismuth quadruple regimen in the treatment of peptic ulcer and its influence on Helicobacter pylori. Methods Eighty-two patients with peptic ulcer treated in our hospital were selected and divided into two groups according to the treatment method, with 41 cases in each group. The control group accepted gentamicin combined with ranitidine treatment, and the observation group was given colloidal bismmth pectin,omeprazole, amoxicillin and clarithromycin treatment. The curative effects and the rates of Helicobacter pylori negative conversion of the two groups were observed. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group（P〈0.05）. The negative rate of Helicobacter pylori in the observation group was significantly higher than that in the control group（P〈0.05）. There was no significant difference in the incidence of adverse reactions between the two groups（P〉0.05）. Conclusion Colloidal bismmth pectin, omeprazole, amoxicillin and clarithromycin in the treatment of peptic ulcer can further relieve the symptoms, eradicate Helicobacter pylori and promote the ulcer healing, and the clinical treatment is of high value.
作者
屈宽顺
QU Kuan-shun(Gastroenterology Department, the Hospital of Luochuan County, Yan＇an 727400, Chin)
出处
《临床医学研究与实践》
2018年第14期23-24,共2页
Clinical Research and Practice
