摘要
目的:观察柴枣龙牡汤治疗糖尿病周围神经病变伴抑郁状态患者临床疗效。方法:将60例患者随机分为2组各30例,观察组予口服柴枣龙牡汤,对照组予口服氟哌噻吨美利曲辛,疗程均为14天,比较2组治疗前后10 g单尼龙丝(10g SWME)异常率、振动阈值定量(VPT)、神经病变主觉症状问卷(TSS)评分、疼痛视觉模拟评分法(VAS)评分、汉密尔顿抑郁量表(HAMD-17)评分及不良反应。结果:治疗后,2组VPT、TSS、VAS、HAMD-17较治疗前均有改善,差异均有统计学意义(P<0.05);组间比较,观察组10g SWME异常率、VPT、TSS、VAS、HAMD-17较对照组均有改善明显,差异均有统计学意义(P<0.05)。结论:本研究采用柴枣龙牡汤治疗糖尿病周围神经病变伴抑郁状态患者安全、有效,与现代医学常规治疗比较,具有明显优势。
Objective： To observe the clinical effect of Chaizao Longmu tang for patients with diabetic peripheral neuropathy with depressive state. Methods：Divided 60 cases of patients into two groups randomly,30 cases in each group.The observation group was given Chaizao Longmu tang orally for treatment,while the control group was given flupentixol and melitracen orally. The treatment lasted for 14 days in both groups. Compared the abnormal rate of 10 g Semmes-Weinstein monofilament examination（10 g SWME）,vibration perception thresholds（VPT）,total symptoms score（TSS）,visual analogue scale（VAS）,Hamilton depression rating scale（HAMD-17） and adverse reactions before and after treatment in the two groups.Results：After treatment,VPT,TSS,VAS and HAMD-17 in the two groups were improved when compared with those before treatment,differences being significant（P〈0.05）. The abnormal rate of 10 g SWME,VPT,TSS,VAS and HAMD-17 in the observation group were improved more obviously than those in the control group, differences being significant（P〈0.05）. Conclusion：The therapy of Chaizao Longmu tang for patients with diabetic peripheral neuropathy with depressive state in this study is safe and effective,which has obvious advantages when compared with routine treatment of modern medicine.
作者
刘远超
谭宏韬
林惠京
刘艺芬
LIU Yuanchao,TAN Hongtao,LIN Huijing,LIU Yifen
出处
《新中医》
CAS
2018年第5期87-90,共4页
New Chinese Medicine
基金
2016年惠州市科技计划(医疗卫生)项目(2016Y114)
