摘要
目的探究采用鼻内镜下低温等离子射频消融术治疗小儿鼾症(OSAHS)的应激反应以及通气功能的影响,为临床提供可靠依据。方法选择2014年5月~2016年6月我院就诊并诊断为小儿鼾症的患儿116例作为研究对象,按照随机数字表法平均分成实验组和参照组,每组各58例。实验组患儿采取鼻内镜下低温等离子射频消融术治疗,参照组患儿采取腺样体刮除术及扁桃体剥离术治疗。对比两组患儿经手术治疗后的应激反应程度、通气功能的影响。结果术后24 h,实验组患儿谷胱甘肽(GSH)以及超氧化物歧化酶(SOD)含量均高于参照组,差异均有统计学意义(P<0.05)。术后6个月,实验组患儿的呼吸缭乱指数(AHI)、氧减指数(ODI)、血氧饱和度<90%所占睡眠时间百分比(SLT90%)以及最长呼吸暂停时间(LAT)均明显低于参照组,最低夜间血氧饱和量(LSa O2)明显高于参照组,差异均有统计学意义(P<0.05)。结论采用鼻内镜下低温等离子射频消融术治疗OSAHS具有显著的临床效果,该手术能缓解患儿术后的应激反应,完善术后的通气功能,值得临床上推广应用。
Objective To explore the effect of nasal endoscopic low temperature plasma ablation in the treatment of children′s snoring stress and ventilation function,to provide a reliable basis for clinical.Methods A total of 116 children with pediatric snoring were selected from May 2014 to June 2016.They were divided into experimental group and reference group according to random number table method,58 cases in each group.The experimental group was treated with low temperature plasma ablation of nasal endoscopy,adenoidectomy and tonsilectomy were used in the reference group.The degree of stress response and the effect of ventilation were compared between the two groups after operation.Results After operation 24 h,the content of glutathione（GSH） and superoxide dismutase（SOD） were higher than that in the reference group,the differences were statistically significant（P〈0.05）.The levels of sleepout（AHI）,oxygen deficit（ODI）,oxygen saturation less than 90% of sleep time（SLT 90%）,and longest apnea were observed 6 months after surgery（LAT） were significantly lower than those in the reference group,the lowest nocturnal oxygen saturation（LSa O2） was significantly higher than that in the reference group,the differences were statistically significant（P〈0.05）.Conclusion The use of nasal endoscopic low temperature plasma ablation in the treatment of pediatric snoring has a significant clinical effect,the operation can relieve the stress response after surgery in children,improve the ventilation after surgery,it is worthy of clinical application.
作者
颜玮宏
蓝建平
李珂
YAN Wei-hong;LAN Jian-ping;LI Ke(Department of Otorhinolaryngology Head and Neck Surgery,ENT Hospital of Longgang District in Shenzhen City, Guangdong Province,Shenzhen 518000,China)
出处
《中国当代医药》
2018年第11期87-89,共3页
China Modern Medicine
关键词
儿童鼾症
低温等离子射频消融术
内镜
应激反应
通气功能
Children＇s snoring
Low-temperature plasma radioffequeney ablation
Endoscopy
Stress response
Ventilation
