摘要
[目的]探讨影响ⅠA-ⅡB期宫颈鳞癌盆腔淋巴结转移的临床病理因素。[方法]回顾性分析接受宫颈癌根治性手术治疗的202例ⅠA-ⅡB期宫颈鳞癌患者的临床病理资料。[结果]盆腔淋巴结总阳性率为16.8%（34/202）。临床分期、肿瘤直径、宫颈间质浸润深度、生长方式、治疗前血SCC-Ag水平与宫颈癌盆腔淋巴结转移密切相关（P〈0.05）;其中,治疗前血SCC-Ag水平（P=0.002）、宫颈间质浸润深度（P=0.033）是影响ⅠA-ⅡB期宫颈鳞癌盆腔淋巴结转移的显著独立危险因素。治疗前血SCC-Ag的最佳预测值为3.05ng/ml。[结论]临床分期、肿瘤直径、宫颈间质浸润深度、生长方式、治疗前血SCC-Ag水平是ⅠA-ⅡB期宫颈鳞癌盆腔淋巴结转移的高危因素。
[Objective]To investigate the clinical and pathological factors of pelvic lymph node metastasis in stage ⅠA-ⅡB cervical squamous cell carcinoma.[Methods]The clinical and pathological data of 202 patients with stageⅠA-ⅡB cervical squamous cell carcinoma treated with radical operation of cervical carcinoma were retrospectively analyzed.[Results]The total positive rate of pelvic lymph nodes was 16.8%（34/202）.Clinical stage,tumor diameter,the depth of cervical interstitial infiltration,growth pattern,and the level of SCC-Ag before treatment were closely related to cervical lymph node metastasis（P〈0.05）.Among them,t he level of SCC-Ag（P=0.002）and interstitial infiltration depth（P=0.033）were significant independent risk factors for pelvic lymph node metastasis of stage ⅠA-ⅡB cervical squamous cell carcinoma.The best predictive value of SCC-Ag before treatment was 3.05 ng/ml.[Conclusion]Clinical stage,tumor diameter,cervical stromal invasion depth,growth pattern,SCC-Ag level before treatment are the high risk factors of pelvic lymph node metastasis in stage ⅠA-ⅡB cervical squamous cell carcinoma.
作者
薛桂各
李胜泽
XUE Gui-ge;LI Sheng-ze(The First Affiliated Hospital of Bengbu Medcical College ,Bengbu 233004 ,Chin)
出处
《肿瘤学杂志》
CAS
2018年第3期250-253,共4页
Journal of Chinese Oncology
