摘要
本文用紫外分光光度法对六个厂家生产的西咪替丁片进行了体外溶出度试验。求得T_(50),T_4等参数具有显著性差异,六个批号只有四批符合美国药典22版规定,且临床使用疗效不一,提示国产西咪替丁片有必要增加溶出度检查以控制其质量。
This paper describes test of dissolution rate of the eimetidine tablets with sp-ectrophotometry. Parameters (T50,Td, etc. ) were defferent significantly. Only fourof the six batches met the requirements of the USP XXII,the curative effectswere different,too. It indicates that it is necessary to make dissolution test forthe cimetidin tablets to control the quality.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1991年第10期457-458,共2页
Chinese Journal of Hospital Pharmacy
关键词
甲氰咪胍
溶出度
分光光度法
Cimetidine
Dissolution rate
UV-spectrophotometry
