摘要
目的探讨蒲公英胶囊联合头孢克洛胶囊治疗扁桃体炎的临床效果。方法选取2016年4月—2017年4月监利县人民医院耳鼻喉科收治的扁桃体炎患者161例为研究对象,将所有患者随机分为对照组(80例)和治疗组(81例)。对照组口服头孢克洛胶囊,1粒/次,3次/d。治疗组在对照组基础上口服蒲公英胶囊,4粒/次,3次/d。两组患者均连续治疗7 d。观察两组的临床疗效,比较两组的临床症状改善、白细胞计数、C反应蛋白和视觉模拟评分法(VAS)评分。结果治疗后,对照组和治疗组的总有效率分别为87.50%、97.53%,两组比较差异具有统计学意义(P<0.05)。治疗后,治疗组发热消退时间、咽部不适消失时间和扁桃体红肿消失时间均明显短于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后,两组白细胞计数、C反应蛋白和VAS评分均显著降低,同组治疗前后比较差异具有统计学意义(P<0.05);且治疗组这些观察指标的下降程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。结论蒲公英胶囊联合头孢克洛胶囊治疗扁桃体炎具有较好的临床疗效,可改善临床症状,降低炎性反应,安全性较好,具有一定的临床推广应用价值。
Objective To investigate the clinical effect of Pugongying Capsules combined with Cefaclor Capsules in treatment of tonsillitis. Methods Patients（161 cases） with tonsillitis in Jianli County People＇s Hospital from April 2016 to April 2017 were randomly divided into the control group（80 cases） and the treatment group（81 cases）. Patients in the control group were po administered with Cefaclor Capsules, 1 grain/time, three times daily. Patients in the treatment group were po administered with Pugongying Capsules on the basis of the control group, 4 grains/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, and clinical symptoms improvement, leucocyte count, C reactive protein, and VAS score in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 87.50% and 97.53%, respectively, and there was difference between two groups（P〈0.05）. After treatment, fever subsided time, pharyngeal discomfort, and tonsil swelling disappeared time in the treatment group were significantly shorter than those in the control group, and there was difference between two groups（P〈0.05）. After treatment, leucocyte count, C reactive protein, and VAS score in two groups were significantly decreased, and the difference was statistically significant in the same group（P〈0.05）. And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups（P〈0.05）. Conclusion Pugongying Capsules combined with Cefaclor Capsules has clinical curative effect in treatment of tonsillitis, can improve clinical symptoms, and decrease inflammatory response, with good safety, which has a certain clinical application value.
作者
杨雅添
郭会义
夏军
YANG Ya-tian, GUO Hui-yi, XIA Jun(Department of Ear-Nose-Throat, Jianli County People＇s Hospital, Jinzhou 433300, Chin)
出处
《现代药物与临床》
CAS
2018年第3期609-612,共4页
Drugs & Clinic
