摘要
目的探讨基于窄带光成像(NBI)的输尿管软镜下治疗肾盂癌的临床效果。方法选择肾盂癌患者62例作为研究对象,根据随机数字表法分为观察组与对照组,各31例。对照组给予常规输尿管软镜下治疗,观察组在对照组治疗的基础上给予术前NBI诊治。结果肾盂癌在白光模式下表现为环形红色黏膜区域,周围有小血管呈放射状排列。在NBI成像模式下表现为棕褐色片状区域,周边有棕褐色放射状小血管。所有患者都顺利完成手术,2组手术时间和术中出血量对比,差异无统计学意义(P>0.05);观察组术后肛门排气时间与术后住院时间明显少于对照组(P<0.05)。观察组术后3个月的血尿、尿瘘、尿路感染、腹膜后感染等并发症发生率为6.5%,对照组为29.0%,观察组术后并发症发生率明显低于对照组(P<0.05)。随访至今,观察组与对照组的中位生存时间分别为(30.42±5.1)个月和(25.39±4.88)个月,差异有统计学意义(t=8.222,P<0.05)。结论基于NBI的输尿管软镜下治疗肾盂癌可最大限度地减少患者手术创伤和术后并发症,延长患者的生存时间,有很好的应用价值。
Objective To investigate the clinical effects of flexible ureteroscope in the treatment of renal pelvic carcino- ma based on narrow-band light imaging （NBI）. Methods 62 patients with renal pelvic carcinoma for diagnosis and treatment were selected as the research object, all the patients were randomly divided into the observation group and the control group with 31 cases in each group, the control group was given conventional treatment of flexible ureteroscope, the observation group was giv- en preoperative NBI diagnosis and treatment based on the control group treatment. Results The renal pelvis carcinoma showed circular red mucosa area by the white light mode, and the small vessels were arranged in radial direction. In the NBI imaging mode, the renal pelvis carcinoma showed brownish, patchy, with small radiating vessels surrounded. All the patients were comple- ted the operation successfully. There were no significant difference compared between the 2 groups in operation time and intraoper- ative blood loss （ P 〉 0.05 ）. The postoperative anal exhaust time and postoperative hospital stay in the observation group were sig- nificantly less than those in the control group （P 〈 0.05 ）. The postoperative 3 months of hematuria, urinary tract infection, urinary fistula,retroperitoneal infection and complication rate in the observation group was 6.5%, so that was 29.0% in the control group, the complication rate in the observation group was significantly lower than the control group （ P 〈 0.05 ）. Up to now, the me- dian survival times in the observation group and the control group were 30.42± 5.11 months and 25.39±4.88 months （ t = 8. 222,P 〈 0.05 ）. Conclusion The flexible ureteroscope in the treatment of renal pelvic carcinoma based on NBI can minimize the surgical trauma,it can reduce the postoperative complications and prolong the survival time of patients.
作者
陆进
王勇
万恩明
诸伟
LU Jin, WANG Yong, WAN Enming,et al.(Wuxi Huishan District People＇s Hospital, Wuxi,21418)
出处
《实用癌症杂志》
2018年第4期671-674,共4页
The Practical Journal of Cancer
关键词
窄带光成像
输尿管软镜
肾盂癌
并发症
Narrow band imaging
Flexible ureteroscope
Renal pelvic carcinoma
Complications
