摘要
目的探讨血清胰岛素样生长因子Ⅱ(IGF-Ⅱ)在宫颈癌中的诊断价值。方法选取2014年5月—2016年12月于苍溪县人民医院妇产科收治的鳞状细胞癌患者90例为宫颈癌组,另选取本院同期正常宫颈组织患者30例为对照组。检测比较两组患者IGF-Ⅱ阳性率。结果宫颈癌组患者IGF-Ⅱ阳性率高于对照组(P<0.05)。高分化患者IGF-Ⅱ阳性率高于中低分化者,临床Ⅱ期患者IGF-Ⅱ阳性率高于Ⅰ期者,淋巴转移患者IGF-Ⅱ阳性率高于无转移患者(P<0.05)。结论检测IGF-Ⅱ对宫颈癌患者的病情诊断、疗效判断、预后评估具有重要的临床意义。
Objective To study the diagnose value of serum insulin-like growth factor Ⅱ（IGF-Ⅱ） in cervical cancer.Methods A total of 90 cases of cervical cancer patients were selected from May 2014 to September 2016 in Cangxi People＇s Hospital as cervical cancer group,30 cases of patients with normal cervical tissue were selected in the same period as control group.The positive rate of IGF-Ⅱ were detected and compared between the two groups.Results The IGF-Ⅱpositive rate of cervical cancer group was higher than control group（P〈0.05）.High differentiation patients of IGF-Ⅱpositive rate was higher than lower differentiation patients,phase Ⅱ patients of IGF-Ⅱpositive rate was higher than phase Ⅰ,lymph node metastasis patients of IGF-Ⅱpositive rate was higher than none-lymph node metastasis（P〈0.05）.Conclusion There is a important clinical significance of IGF-Ⅱ detection in the diagnosis,curative effect judgement,evaluating of cervical cancer.
出处
《临床合理用药杂志》
2018年第3期22-23,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
宫颈肿瘤
胰岛素样生长因子Ⅱ
淋巴转移
Uterine cervical neoplasms
Insulin- like growth factor Ⅱ
Lymph node metastases
