摘要
目的探讨地佐辛联合山莨菪碱与盐酸哌替啶肌肉注射治疗输尿管结石性肾绞痛的镇痛效果和不良反应。方法将180例肾绞痛患者随机分为A、B、C组,每组60例。A组肌肉注射地佐辛5 mg,B组肌肉注射地佐辛5 mg和山莨菪碱10 mg,C组肌肉注射盐酸哌替啶100 mg。观察三组患者疼痛缓解情况及不良反应发生情况。结果用药后15、30 min,B组镇痛效果总有效率明显高于A、C组(P<0.05)。A、B组不良反应总发生率明显低于C组(P<0.05)。结论肌肉注射地佐辛联合山莨菪碱止痛效果优于单用地佐辛和盐酸哌替啶,镇痛作用快,不良反应发生率低,安全性高,值得在临床推广。
Objective To observe the analgesic effect and adverse reactions of intramuscular injection of dezocine combined with anisodamine in ureteral calculi with renal colic. Methods A total of 180 cases of patients with ureteral calculi with renal colic were randomly divided into A, B, C groups, with 60 cases in each group. Group A was given intramuscular injection of dezocine 5 mg, and group B received intramuscular injection of dezocine 5 mg and anisodamine 10 mg, while group C accepted intramuscular injection of pethidine hydrochloride 100 mg. The pain relief and adverse reactions of the three groups were observed. Results After medication for 15, 30 min, the total effective rate of analgesic effect in the group B were higher than that of the group C(P<0.05). The total inicidences of adverse reations of the group A and B were lower than that of the and group C(P<0.05). Conclusion The intramuscular injection of dezocine combined with anisodamine has better analgesic effect than that of use of with dezocine or pethidine hydrochloride, which has good analgesia, low incidence of adverse reactions and high safety. It is worth to be popularized in clinical practice.
出处
《临床医学研究与实践》
2018年第7期50-51,共2页
Clinical Research and Practice
关键词
地佐辛
山莨菪碱
盐酸哌替啶
肾绞痛
dezocine
anisodamine
pethidine hydrochloride
renal colic
