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猪圆环病毒疫苗在规模化猪场的使用效果研究 被引量:4

Clinical immune efficacy of porcine circovirus vaccines in a large-scale pig farm
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摘要 为了比较分析湖北省某规模化猪场猪圆环病毒亚单位疫苗和全病毒灭活疫苗的使用效果,选择21日龄健康仔猪1 000头,随机分为3组,每组330-336头,分别免疫亚单位疫苗(A组)、灭活疫苗(B组)和生理盐水(C组);免疫后30、60和90 d,通过检测猪只的生产性能、抗体水平和血清中病毒含量来比较2种疫苗的免疫效果。结果显示:相比较于生理盐水组,2种疫苗免疫商品猪后,均能显著提高日增重(P〈0.05),降低死淘率和肉料比,提高血清抗体水平和减少排毒。而且,亚单位疫苗的免疫效果优于目前的常规灭活疫苗,值得推广应用。 The vaccine immunization is the most direct and efficient method to prevent and control porcine circovirus disease(PCVD). In order to compare the immune effecacy of porcine circovirus 2(PCV2) subunit vaccine and inactivated vaccine in a large scale pig farm from Hubei province,1 000 healthy piglets of 21 day-old were randomly divided into three groups and each group had 330 to 336 piglets. Three groups were innoculated with the subunit vaccine(A group),inactivated vaccine(B group) and normal saline(group C),respectively,and sampled for detection of production performance,antibody level and serum virus content at 30,60 and 90 days after immunization. The results showed that compared with the normal saline group,two kinds of vaccine immunized pigs could increase daily gain,reduce the death rate and the ratio of feed to meat,increase serum antibody level and reduce virus shedding. And the immune efficacy of subunit vaccine was better than that of the inactivated vaccine.
出处 《畜牧与兽医》 北大核心 2018年第2期97-99,共3页 Animal Husbandry & Veterinary Medicine
关键词 猪圆环病毒 亚单位疫苗 灭活疫苗 免疫效果 porcine circovirus subunit vaccine inactivated vaccine immune efficacy
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