摘要
目的探讨成人慢性咳嗽的病因和治疗效果。方法选取2015年10月—2016年9月在解放军白求恩国际和平医院呼吸内科门诊就诊符合纳入及排除标准的成人慢性咳嗽109例为研究对象,参照"咳嗽的诊断与治疗指南(2009版)"中的诊治方法进行诊断与治疗,分析其病因及治疗效果。结果 109例中96例慢性咳嗽最后明确诊断,其中单一病因89例,双重病因6例,三重病因1例;13例慢性咳嗽病因不明。96例明确诊断的慢性咳嗽前3位病因是咳嗽变异性哮喘、上气道咳嗽综合征和变应性咳嗽。女性慢性咳嗽患者咳嗽变异性哮喘发病率明显高于男性慢性咳嗽患者,差异具有统计学意义(P<0.05);6例血管紧张素转换酶抑制剂诱发年龄均>50岁。经治疗后,109例中78例治愈(71.6%),29例有效(26.6%),2例无效(1.8%),总有效率为98.2%。结论咳嗽变异性哮喘、上气道咳嗽综合征和变应性咳嗽是导致慢性咳嗽的常见病因,慢性咳嗽病因中咳嗽变异性哮喘患者女性多于男性,多数慢性咳嗽治疗有效。
Objective To analyze causes and treatment effect of adult patients with chronic cough. Methods A total of 109 adult outpatients with chronic chough during October 2015 and September 2016,who had met the inclusion criteria,were recruited in the study. On the basis of Guideline on Diagnosis and Treatment of Cough( 2009 edition),the patients were diagnosed and treated,and then the causes and treatment effects were analyzed. Results Among the 109 outpatients,96 patients were confirmed the diagnosis of chronic chough,in which 89 patients had a single cause,6 patients had two kinds of causes and 1 had three kinds of causes; other 13 patients with chronic chough showed etiology unknown. The top three causes of chronic cough in the 96 confirmed patients were cough variant asthma( CVA),upper airway cough syndrome( UACS) and atopic cough( AC). Incidence rate of CVA in female patients with chronic chough was significantly higher than that in male patients with chronic chough( P < 0. 05). The age of 6 cough patients induced by angiotensin converting enzyme inhibitor was more than 50 years old. After treatment,78 patients( 71. 6%) were cured,29 patients( 26. 6%) were effective,and 2 patients were noneffective in the 109 patients,and the total effective rate was 98. 2%. Conclusion CVA,UACS and AC are the most common reasons of chronic cough. CVA is more frequently found in females that that in males,and most treatments for chronic cough are effective.
出处
《临床误诊误治》
2018年第2期43-46,共4页
Clinical Misdiagnosis & Mistherapy
关键词
咳嗽
病因
治疗结果
Cough
Cause of disease
Treatment outcome