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Epstein-Barr病毒相关淋巴瘤的研究进展 被引量:2

Research advances in Epstein-Barr virus-associated lymphoma
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摘要 Epstein-Barr病毒(Epstein-Barr virus,EBV)是第1个被发现与人类肿瘤发生相关的病毒,且越来越多的数据表明其感染与某些淋巴瘤的发生发展、治疗及预后密切相关。近年来免疫治疗技术发展迅速,但EBV阳性淋巴瘤的治疗目前仍主要以放化疗为基础,结合抗病毒药物。因此,加强EBV及其相关淋巴瘤的研究,寻找有效预防或治疗EBV感染的方法,将有望改善EBV阳性淋巴瘤患者的预后。 Epstein-Barr virus(EBV) is one of the human viruses found to be associated with tumorigenesis.Studies have demonstrated that EBV infection is closely related with the occurrence,development,treatment and prognosis of lymphomas.To date,although the application of antiviral drugs and immunotherapy is rapidly developed,the treatment against EBV-positive lymphomas is still mainly based on radiotherapy and chemotherapy.To strengthen the research on EBV and EBV-related lymphomas will improve the prognosis of patients with EBVpositive lymphomas.
作者 谷晓宇 谢彦晖 GU Xiaoyu;XIE Yanhui(Huadong Hospital Affiliated to FudanUniversity,Shanghai 200040, Chin)
出处 《微生物与感染》 2018年第1期2-7,共6页 Journal of Microbes and Infections
关键词 EPSTEIN-BARR病毒 淋巴瘤 治疗 预后 Epstein-Barr virus Lymphoma Treatment Prognosis
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