摘要
目的观察运用培土生金法治疗小儿哮喘缓解期肺脾气虚证的临床疗效。方法选取2015年11月至2016年11月于我院儿科就诊的哮喘缓解期肺脾气虚证患儿138例,随机分为治疗组和对照组,各69例。对照组予以西药治疗,治疗组给予自拟益脾固肺汤治疗,治疗3月后比较2组的临床症状、血清学指标及肺功能的变化。结果治疗组总有效率为82.6%,对照组为66.7%,2组比较差异有统计学意义(P<0.05)。2组治疗前肿瘤坏死因子-α(TNF-α)、嗜酸性粒细胞计数(EOS)及免疫球蛋白E(IgE)水平比较,差异无统计学意义(P>0.05);治疗后2组TNF-α,EOS及IgE水平均较同组治疗前明显下降(P<0.05),且治疗组下降更显著(P<0.05)。2组治疗前第1秒用力呼气量(FEV_1)、最大呼气流速(PEF)水平比较,差异无统计学意义(P>0.05);治疗后2组FEV_1,PEF水平均较同组治疗前明显升高(P<0.05),且治疗组肺功能改善情况明显优于对照组(P<0.05)。结论培土生金法不仅可以明显缓解小儿哮喘缓解期肺脾气虚证的临床症状,还能改善患儿呼吸道通气功能,明显抑制呼吸道炎症反应,提高患儿自身免疫力,起到既病防变的效果。
Objective To observe the effect of infantile asthma（ deficiency of lung and spleen qi syndrome） in remission treated with strengthening earth to support metal method. Methods 138 cases of children with asthma（ deficiency of lung and spleen qi syndrome） in remission from Nov.2015 to Nov.2016 in our hospital were randomly divided into two groups with 69 cases in each. The control group was treated with conventional Western medicine,while the therapy group was given self-made Yipi Gufei Tang.All patients were treated for 3 months.The differences of clinical symptoms,serological indexes and pulmonary function between the two groups were observed and compared.Results The total effective rate in control group and therapy group was 66.7% and 82.6% respectively with significant differences（ P〈0.05）; differences of degrees of TNF-α,EOS and Ig E in two groups before treatment had no significance（ P 〉 0. 05）; after treatment,these dropped obviously comparing with these before treatment（ P 〈0.05）,but these reduced obviously in therapy group（ P〈0.05）.There were no significant differences in the levels of PEF,FEV1 of two groups before treatment（ P〉0.05）,but after treatment,these in two groups increased obviously（ P〈0.05）,and the lung function improved more in therapy group than that in control group.Conclusion Strengthening earth to support metal method not only can alleviate clinical symptoms of infantile asthma（ deficiency of lung and spleen qi syndrome） in remission,but also improve ventilatory function of patients’ respiratory tract by suppressing inflammation and improving self-immunity to prevent disease becoming worse.
出处
《中医儿科杂志》
2018年第1期29-32,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
小儿哮喘
缓解期
培土生金法
益脾固肺汤
临床观察
infantile asthma
remission
strengthening earth to support metal method
Yipi Gufei Tang
clinical observation
