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超声内镜引导下细针穿刺对胰腺癌的诊断价值 被引量:11

Diagnostic value of endoscopic ultrasonography guided fine needle aspiration in patients with pancreatic cancer
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摘要 目的探讨超声内镜引导下细针穿刺(endoscopic ultrasonography fine needle aspiration,EUS-FNA)对胰腺癌的临床诊断价值及其安全性。方法收集2015年7月至2017年1月武汉大学人民医院消化内科临床诊断及影像学疑诊胰腺癌患者35例的临床资料。超声内镜(endoscopic ultrasonography,EUS)发现病变后,在实时超声引导下用EUS-FNA。结果 35例患者中男23例,女12例,年龄46~80岁,12例位于胰头部,5例位于胰颈部,8例位于胰体部,10例位于胰尾部。EUS-FNA诊断胰腺癌的敏感度为91%,特异度为100%,阳性预测值为100%,穿刺病理学阳性率为88%(31/35)。无一例出现急性胰腺炎、胰周感染、腹腔内大出血等严重并发症。结论 EUS-FNA是安全有效的操作,对胰腺癌的诊断有较高价值,值得推广。 Objective To investigate the clinical characteristics of pancreatic cancer and the diagnostic value of endoscopic ultrasonography fine needle aspiration( EUS-FNA) in patients with pancreatic cancer. Methods EUS-FNA was performed in 35 patients with pancreatic lesions detected by CT scanning,ultrasonography or clinically suspected diagnosis. Results There were 23 males and 12 females patients with the age ranging from 46 to 80 years old. Twelve cases located in pancreatic head,5 cases in pancreatic neck,8 cases in pancreatic body,10 cases in pancreatic tail. The sensitivity,specificity and positive predictive value of EUS-FNA were 91%,100% and 100%,respectively. The positive rate of histopathology and cytopathology was 88%( 31/35). EUS-FNA was conducted on all 35 patients without any serious complications,such as acute pancreatitis,pancreatic infection,intra-abdominal bleeding. Conclusion EUSFNA for the pancreas is a safe and effective modality for diagnosis and treatment of pancreatic cancer.
作者 石娟 董卫国
出处 《胃肠病学和肝病学杂志》 CAS 2018年第1期39-42,共4页 Chinese Journal of Gastroenterology and Hepatology
关键词 超声内镜 细针穿刺 胰腺癌 Endoscopic uhrasonography Fine needle aspiration Pancreatic cancer
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