摘要
目的探讨盆底器官脱垂（pelvic organ prolapse,POP）新式手术和传统手术对患者凝血功能的影响。方法盆底器官脱垂92例患者,44例行新式手术,48例行传统手术,对年龄、BMI、分期、高血压、糖尿病、手术时间、出血量及术前1个月内、术后第2天的红细胞比积（HCT）、纤维蛋白原定量（FIB）、凝血酶原时间及活动度（PT）、凝血酶凝结时间（TT）、国际标准化比值（INR）、活化部分凝血活酶时间（APTT）和D-二聚体（D-D）,及手术前后血小板（PLT）和血红蛋白（Hgb）比较。结果传统手术与新式手术组术后凝血功能中FIB、PT及HCT差异有统计学意义（P〈0.05）;在传统组术前与术后比较中,FIB、PT、TT、INR、D-D、HCT及PLT差异均有统计学意义（P〈0.05）;在新式组术前与术后比较中,FIB、PT、TT、INR、D-D、HCT、APTT、D-D、HCT及PLT差异均有统计学意义（P〈0.05）;传统组与新式组手术前后血常规Hgb和PLT变化差异无统计学意义（P〉0.05）。结论网片植入对患者手术凝血功能有一定程度的影响,但并未引起严重并发症。
Objective To investigate the clinical coagulation function changes during the operation in pelvic organ prolapsed women.Methods 92 pelvic organ prolapsed patients were collected,48 subjects treated with traditional operations and 44 subjects with pelvic floor reconstruction operations.The coagulation function were evaluated before surgery within one month and in the second day after surgery,and the clinical data were analyzed separately such as Hct,PLT,Hgb,FIB,PT,TT,INR,APTT and D-D.Results There were significant differences in the coagulation function before and after surgery,including FIB,PT and HCT（P 〈0.05）.In traditional operation group,there were significant differences in FIB、PT、TT、INR、D-D、HCT and PLT before and after surgery（P〈 0.05）.In pelvic floor reconstruction operation group,there were significant differences in FIB、PT、TT、INR、D-D、APTT、HCT and PLT（P 〈0.05）before and after surgery.Interestingly,there was no significant difference of Hgb and PLT before and after surgery（P 〉0.05）.Conclusion There were a certain extent effects on the clinical coagulation function during pelvic floor reconstruction operation,with no severe complications.
出处
《中国妇产科临床杂志》
CSCD
北大核心
2018年第1期33-35,共3页
Chinese Journal of Clinical Obstetrics and Gynecology
关键词
盆底器官脱垂
新式手术
传统手术
凝血功能
pelvic organ prolapsed
pelvic floor reconstruction operation
traditional operation
coagulation function
