摘要
目的结合流行病学分析方法对凉山州2011-2015年艾滋病哨点吸毒人群艾滋病病毒(HIV)感染疫情进行分析,为制定当地艾滋病的防治策略提供科学依据。方法 2011-2015年,在凉山州7个国家级吸毒人群艾滋病监测哨点中,每年4-6月抽取口服、吸入和注射毒品的个体为监测对象。采用问卷调查收集人口学特征和相关行为特征信息。采用酶联免疫吸附试验和蛋白印迹试验进行HIV抗体阳性检测。采用SPSS 19.0统计学软件进行数据分析。结果 2011-2015年,共监测有效对象10 003人。2011-2015年,HIV阳性检出率分别为19.15%(449/2 345)、19.11%(369/1 931)、22.32%(431/1 931)、21.62%(411/1 901)、15.83%(300/1 895)。分析发现彝族[比值比(OR)=2.31,95%可信区间(CI):1.87~2.86]、共用针具(OR=8.60,95%CI:7.59~9.73)、文化程度低(初中vs高中及以上:OR=1.39,95%CI:0.97~2.01;小学或文盲vs高中及以上:OR=2.26,95%CI:1.60~3.19)能增加吸毒者感染HIV的风险;女性(OR=0.80,95%CI:0.68~0.94)和有固定性伴(OR=0.87,95%CI:0.76~0.99)感染HIV的风险比男性和没有固定性伴者低,年龄在51~70岁(OR=0.37,95%CI:0.23~0.60)感染HIV的风险较低。结论凉山彝族自治州吸毒人群HIV抗体阳性率较高,HIV在该人群中流行趋势严峻。
Objective To understand the HIV infection and epidemiology among drug users of Liangshan prefecture between 2011 and 2015,so as to provide scientific basis to formulate AIDS prevention and control strategies.Methods There were seven sites of the national AIDS sentinel surveillance of drug users,including oral,inhaling and injecting drug users and a questionnaire investigation was conducted each year between April and June for the surveillance during 2011-2015 to collect the demographic and behavior related information.Anti-HIV ELISA and WB methods were used to detect HIV.SPSS 19.0 was used to perform statistical analyses.Results 10 003 drug users were included in the investigation.The positive rates of the five years were 19.15%（449/2345）,19.11%（369/1931）,22.32%（431/1931）,21.62%（411/1901）,and 15.83%（300/1895）respectively.The factors which increased the risks of HIV infection included Yi ethnic people（OR=2.33,95% CI：1.87-2.86）,needle sharing（OR =8.60,95% CI：7.59-9.73）,low level of education（secondary vs high school or above：OR=1.39,95% CI：0.97-2.01;primary school or below vs high school or above：OR=2.26,95% CI：1.60-3.19）,and awareness of HIV related knowledge（OR=1.43,95%CI：1.173-1.753）.The protective factors of HIV infection included females,regular sex partners and age above 51-70 years.Conclusion The infection rate of HIV among drug users is high,and HIV epidemic is serious in this population.
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2017年第12期1107-1110,共4页
Chinese Journal of Aids & STD
基金
国家自然科学基金(81703279)
四川省卫生和计划生育委员会科研课题(16PJ259)
凉山州艾滋病防治项目(H161236)
凉山州艾滋病新发感染评估模式探索项目(2014LSCDC002)~~
关键词
吸毒
艾滋病病毒
哨点
凉山
彝族
[）rug users
HIV
Liangshan prefecture
Yi people
