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肝门部胆管癌临床治疗的研究进展 被引量:17

Advances in clinical treatment of hilar cholangiocarcinoma
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摘要 肝门部胆管癌是指原发于胆囊管开口以上的肝总管及左、右肝管起始部或者汇合部的一类恶性肿瘤。其起病隐匿,早期难以发现,且极易侵犯肝脏以及周围的血管、神经、淋巴结,因而预后较差。近年来,随着研究的深入、影像学技术不断进步和各种治疗方法的涌现与改进,肝门部胆管癌的临床治疗研究取得了较大进展。目前,其治疗手段包括手术切除、肝移植、姑息性胆道引流、放疗、化疗、光动力疗法、生物靶向治疗等,其中手术切除仍是唯一可能治愈肝门部胆管癌的手段。本文就近年来肝门部胆管癌的临床治疗研究进展做一综述,以期为临床上选择最佳治疗方案提供参考依据。 Hilar cholangiocarcinoma refers to a kind of malignancy in the duetuli hepaticus communis and the main left or right hepatic duct or their confluence. It is hard to be found in the early stage because of insidious onset and is liable to in- vade surrounding blood vessels, nerves, lymph nodes. Hence it has a poor prognosis. In recent years, with the in-depth research as well as the development of imageology and methods of treat- ment, considerable achievements have been made in treatment of hilar cholangiocarcinoma. At present, the treatment methods in- clude surgical resection, liver transplantation, palliative biliary drainage, radiotherapy, chemotherapy, photodynamic therapy and targeted therapy, etc. Surgical resection remains the only curative treatment option. This article reviews the research pro- gress in treatment of HC in order to provide the reference for se- lection of the optimal treatment program.
作者 唐明尧 陈勇
出处 《中华肝胆外科杂志》 CSCD 北大核心 2017年第12期857-860,共4页 Chinese Journal of Hepatobiliary Surgery
基金 国家自然科学基金(81670563)
关键词 肝门部胆管癌 治疗 Klatskin Hilar cholangiocarcinoma Treatment Klatskin tumor
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