摘要
目的探讨人参养荣汤联合肠内营养对中晚期结肠癌患者化疗期间营养状况的影响。方法将80例中晚期结肠癌患者分为观察组和对照组各40例。化疗期间,两组均给予肠内营养,观察组同时给予中药人参养荣汤口服。化疗前及第1疗程结束后,比较两组患者的血清ALB、血清总蛋白(TP)、血清前蛋白(PA)、体质量指数(BMI)、肱三头肌皮褶厚度(TSF)、上臂肌围(AMC)、Hb水平。结果化疗后对照组ALB、TP、PA、BMI、TSF、AMC、Hb均低于化疗前及观察组(P<0.05),而观察组各项指标与化疗前比较,差异无统计学意义(P>0.05)。结论在肠内营养的基础上,使用人参养荣汤有利于改善中晚期结肠癌患者化疗期间的营养状况。
Objective To investigate the effect of ginseng decoction for nourishing combined with enteral nutrition on nutritional status during chemotherapy in patients with middle-stage or advanced colon cancer. Methods Eighty patients with middle-stage or advanced colon cancer were divided into observation group and control group,with 40 cases in each group. Both groups received enteral nutrition during chemotherapy. And the observation group was also orally administered ginseng decoction for nourishing. Before chemotherapy and after the first course of chemotherapy,serum levels of ALB,total protein（ TP） and prealbumin（ PA）,body mass index（ BMI）,brachial triceps skinfold thickness（ TSF）,upper arm muscle circumference（ AMC）,and Hb level were compared between the two groups. Results After chemotherapy,the levels of ALB,TP,PA and Hb,BMI,TSF,and AMC in the control group were lower than those before chemotherapy or in the observation group（ P〈0. 05）. But no significant differences were found between those indices above before and after chemotherapy in the observation group（ P 0.05）. Conclusion Administration of ginseng decoction for nourishing is benefit to the improvement of nutritional status during chemotherapy in patients with middle-stage or advanced colon cancer on the basis of enteral nutrition.
出处
《广西医学》
CAS
2017年第12期1777-1780,共4页
Guangxi Medical Journal
基金
军队中医药专项课题(10zyz241)
关键词
结肠癌
化疗
人参养荣汤
肠内营养
营养状况
Colon cancer,Chemotherapy,Ginseng decoction for nourishing,Enteral nutrition,Nutritional status
