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缩宫素鼻喷雾剂在产后止血和催乳中的疗效评价 被引量:6

Efficacy of Oxytocin Nasal Spray in Postpartum Hemostasis and Lactation
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摘要 目的:探讨缩宫素鼻喷剂在产妇产后出血和催乳中的疗效。方法:选取我院2016.06—2017.10收取的120例产妇为研究对象,随机分为对照组和观察组,每组60例。对照组产妇前3d给予婴儿吸吮鼓励,6次/d;观察组产妇在常规鼓励婴儿吸允的基础上,另外给予缩宫素鼻喷剂处理,对比分析两组产妇产后24h的出血量以及奶汁的分泌情况。结果:观察组产妇产后24h的出血量为(176.78±18.90)m L,对照组产妇产后24h的出血量为(265.70±22.60)m L,观察组产妇产后24h的出血量显著低于对照组,差异有统计学意义,P<0.05;观察组产妇产后46例奶汁充足(76.67%),11例奶汁不足(18.33%),3例无奶汁(5.00%);对照组产妇产后32例奶汁充足(53.33%),19例奶汁不足(31.67%),9例无奶汁(15.00%),观察组产后奶汁充足产妇显著高于对照组产妇,两组产妇产后奶汁分泌情况的差异有统计学意义,P<0.05。结论:缩宫素鼻喷剂能显著降低产妇产后的出血量,增加奶汁的分泌量,值得临床推广应用。 Objective To investigate the curative effect of oxytocin nasal spray on postpartum hemorrhage and lactation. Methods: 120 maternalwomen from 2016.06 to 2017.10 in our hospital were selected as study subjects and randomly divided into control group and observation group with60 cases in each group. In the control group, mothers were encouraged to suck 6 times/day. In the observation group, on the basis of conventionalencouragement of infants, oxytocin nasal spray was additionally administered to the observation group. Comparative analysis of 2 groups ofpostpartum 24 hours postpartum bleeding and milk secretion was performed. Results: The amount of bleeding at 24h after delivery in the observationgroup was (176.78±18.90) mL, while that in the control group was (265.70±22.60) mL. The amount of bleeding at 24 hours after delivery in theobservation group was significantly lower than that of the control group (P〈0.05). The observation group maternal postpartum 46 cases of adequatemilk (76.67%), 11 cases of insufficient milk (18.33%), 3 cases without milk juice (5.00%), the control group postpartum 32 cases of milk (53.33%),19 cases of lack of milk (31.67%), 9 cases of non-milk juice (15.00%), the observation group postpartum adequate milk production was significantlyhigher than the control group maternal, there were significant differences in postpartum milk secretion among the two groups, P〈0.05. Conclusion:Oxytocin nasal spray can significantly reduce the amount of postpartum hemorrhage and increase the amount of milk secretion, which is worthy ofclinical application.
作者 陈媛 CHEN Yuan(Xiamen university affiliated Fuzhou second hospital, Xiamen Fujian 350007, Chin)
出处 《药品评价》 CAS 2017年第24期41-43,57,共4页 Drug Evaluation
关键词 缩宫素鼻喷剂 产妇 出血量 催乳 Oxytocin Nasal Spray Maternal Bleeding Prolactin
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