摘要
目的:探讨慢性阻塞性肺疾病(COPD)与骨质疏松症的相关性及临床意义。方法:选取老年男性COPD患者50例与同龄健康体检者50例,分别测定两组人群的骨密度(BMD)及相关骨代谢指标[血钙(Ca^(2+))、血磷(P)、25(OH)D_3、甲状旁腺激素(PTH)及碱性磷酸酶(ALP)],进行对比及分析。结果:COPD组患者的BMD、血钙(Ca^(2+))、血磷(P)、及25(OH)D_3指标明显低于对照组(P<0.05),PTH高于对照组(P<0.05),而ALP在两组间差异无统计学意义(P>0.05)。结论:COPD患者并发骨质疏松发生率较高,在临床诊疗中应引起高度重视。
Objective:To investigate the correlation between chronic obstructive pulmonary disease(COPD)and osteoporosis and its clinical significance.Methods:Fifty elderly male COPD patients were selected and compared with 50 healthy people.The bone mineral density(BMD)and related bone metabolic index [Ca^(2+),P25(OH)D_3,PTH and Alkaline and phosphatase(ALP)]differences.Results:The levels of BMD,Ca^(2+),P,and 25(OH)D_3 in COPD group were significantly lower than those in control group(P<0.05),PTH was higher than control group(P<0.05)with Statistical significance(P>0.05).Conclusion:The incidence of osteoporosis in patients with COPD is high,which should be paid more attention in clinical diagnosis and treatment.
出处
《陕西医学杂志》
CAS
2018年第1期14-16,共3页
Shaanxi Medical Journal
基金
陕西省科技厅科技惠民专项(2013K14-02-09)
关键词
词肺疾病
慢性阻塞性/并发症
骨质疏松/病因学
骨密度
Lung disease
Chronic obstructive/complications
Osteoporosis/etiology
Bone mineral density
