摘要
2013年全球疾病负担研究报道指出COPD和肺癌皆是全球六大非传染性疾病死亡原因之一。近年来越来越多的研究认为这两种疾病存在相同的危险因素,如吸烟、气道炎症、遗传易感性等,且一些流行病学研究发现,COPD患者发生肺癌的风险会明显提高。在本文中,我们简要综述了两者潜在的关系及相关机制研究。
In 2013, the global burden of disease study reported that COPD and lung cancer were two of the world's six most common causes of death. In recent years, studies have shown that COPD and lung cancer share similar risk factors, such as smoking, airway inflammation, genetic predisposition, etc. Epidemiological studies have found that COPD patients had a higher risk to develop lung cancer in contrast non-COPD patients. In this paper, we briefly reviewed studies published regarding the underlying relationship and the pathogenesis between COPD and lung cancer.
出处
《国际呼吸杂志》
2017年第23期1832-1836,共5页
International Journal of Respiration
关键词
慢性阻塞性肺疾病
肺癌
致病因素
机制
Chronic obstructive pulmonary disease
Lung cancer
Pathogenic factors
Mechanism