摘要
目的观察三联法对霉菌性食管炎的疗效。方法本组450例均经电子胃镜检查、病理证实,并依霉菌对食管粘膜损害程度将其分为重度、中度、轻度,分别予三联法口服(洛赛克+盐酸黄连素+西沙必利)250例,单服克霉唑100例,食用生大蒜100例。各组治疗均依每10d为1疗程,若无毒副反应可连用2疗程,并经内镜、病理复检无再显示霉菌者为治愈。结果三联法治愈率为98%、克霉唑为53%、食用大蒜为54%。对比结果显示三联法显著优于其他两组(P<0.01),而克霉唑与食用大蒜组比较无显著性差异(P>0.05)。结论应用三联法治疗霉菌性食管炎疗效可靠,治愈率高,疗程短且无毒副反应。
Objective To investigate the curative effect of triad -therapy for mycotic esophagitis.Methods The450cases were all given electronic gastroscopy and certified by pathological examination,and divided into three groups(the severe,the moderate and the mild)according to the extent of mycotic esophageal mucosa damage.For the severe group(250cases),triad -therapy(Losec+Berberine hydrochloride+Cisapride)was adopted;the moderate group,100cases,Clotrimazole only and the mild group,100cases,raw garlic,10days as one course of treatment,and next course could be continued if there were no toxic and side reaction.It was certified cure if there were no mycotic showing through eleotronic gastroscopy and pathological examination.Results The cure rate was98%in the triad-therapy group,53%in the Clotrimazole group,54%in the garlic-eaten group.The curative effect in the triad-therapy group was much better than that in other two groups(P<0.01),while the difference between latter two groups wasn't sign ificant(P>0.05).Conclusion Triad-therapy for mycotic esophagitis is reliable in cure effects,high in cure rate,short in treatment course,and has no side effects
出处
《实用医药杂志》
2002年第8期561-562,564,共3页
Practical Journal of Medicine & Pharmacy
