摘要
目的:分析医院多重耐药菌(MDRO)的分布趋势及其耐药性,为医院感染防控及干预措施的实施提供参考。方法:目标性监测2013年—2015年间医院患者中分离出的MDRO,分析其分布及其对抗菌药物的耐药性。结果:3年间抽检MDRO菌株4 671株,其中耐药菌株748株(2003年为148株,2014年为282株,2015年为318株)占总检出率为16.01%,呈现逐年上升趋势,主要以耐甲氧西林金黄色葡萄球菌(MRSA)居高;MDRO标本来源以痰液为主(占63.94%),其主要分布在重症监护病房(ICU)、烧伤科和神经外科。结论:ICU、烧伤科和神经外科是MDRO感染日趋严重科室,应立即采取有效地预防控制措施,遏制或降低MDRO的感染和流行。
Objective： To analyze the distribution and drug resistance of multidrug-resistant organisms in our hospital during 2013 to 2015, and to provide guidance for prevention and intervention of the MDRO infections. Methods： The targeted surveillance was carried out for all patients＇ isolated MDRO in our hospital during 2013 to 2015, and its distribution and antimicrobial drug resistance were analyzed. Results： The 4 671 strains of MDRO were detected in three years, among them, the resistant strains 748 strains of total detection rate were 16.01%（2013 was 148, 2014 was 282, and 2015 was 318 strains）. The drug-resistant strains showed a trend of rising year by year. Methicillin-resistant Staphylococcus aureus （MRSA） was in the first place. Source of MDRO specimen was given priority to with sputum （63.94%）. MDRO were mainly distributed in the intensive care unit （ICU）, burn surgery and neurosurgery. Conclusion： The MDRO infection has become increasingly serious in the intensive care unit （ICU）, burn surgery and neurosurgery. The effective prevention and control measures should be quickly taken to reduce MDRO infection and popularizing.
出处
《抗感染药学》
2017年第7期1325-1328,共4页
Anti-infection Pharmacy
关键词
MDRO
目标性监测
干预
措施
multidrug-resistant organisms（MDRO）
targeted surveillance
drug resistance
