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重组脑钠肽治疗顽固性心力衰竭的疗效及对血流动力学、心功能的影响 被引量:11

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摘要 目的探讨重组脑钠肽(rh BNP)治疗顽固性心力衰竭的疗效及对血流动力学、心功能的影响。方法顽固性心力衰竭患者56例,回顾性分析其治疗方法及实验室检查结果,分为接受常规治疗的对照组29例、接受常规治疗+rh BNP治疗的观察组27例。评估两组治疗效果;采用Swan-Ganz漂浮导管测定血流动力学参数水平;应用彩色多普勒超声仪测定心功能参数水平。结果治疗前,两组血流动力学参数、心功能参数水平差异无统计学意义(P>0.05)。治疗1 w后,观察组治疗总有效率高于对照组(P<0.05);观察组血流动力学指标中心静脉压(CVP)、右房压(RAP)、肺毛细血管楔压(PCWP)水平低于对照组(P<0.05);观察组心功能参数左室收缩末期内径(LVESD)、左室舒张压末期内径(LVEDD)水平低于对照组,左室射血分数(LVEF)水平高于对照组(P<0.05)。结论 rh BNP可改善顽固性心力衰竭患者心功能、优化血流动力学状态。
出处 《中国老年学杂志》 CAS 北大核心 2017年第22期5585-5587,共3页 Chinese Journal of Gerontology
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