摘要
高原地区的环境特点为低压、低氧、低温。人群进入这种环境,多数经过自身调节后很快适应,不会对机体造成明显损害。但部分人群不能适应高原的低氧环境,易发生急性高原病(AMS),主要包括高原肺水肿、高原脑水肿等。伴随西部大开发战略,国家将青海省可可西里地区申请为世界自然遗产保护区,这会吸引更多国内外游客进入高海拔地区,从而为高原医学工作者提出严峻的考验。目前,相关研究多以人群直接进入高海拔地区前后的相关血液因子变化作为研究对象,而缺乏对亚高原地区适应过程的观察研究。因此,研究健康人群由低海拔地区经过亚高原的预适应再进入高原地区的血液因子表达,将为AMS的诊断及预防提供有效措施。
The environmental characteristics of the plateau area are low pressure, low oxygen and low temperature. When human get into this environment, most people quickly adapt to the environment through the self-regulation, with no significant damage to the body. However, a few people cannot adapt to the plateau hypoxic environment, and they are prone to suffer from acute mountain sickness （ AMS）, mainly including high-altitude pulmonary edema, high altitude cerebral edema etc. Following the strategy to develop the western regions, Hoh Xil applied as nature reserve of World Natural Herit- age Reserve, which will attract more and more tourists from all the world, presenting a great challenge for the plateau medical staff. At present, the relevant researches are mostly about the relevant changes in blood factors of the population who directly got into the high altitude area, but lack of observation research on the adaptation process of sub-plateau area. Therefore, the study of blood factor expression of healthy population from low altitude areas through the sub-plateau pre-adaptation and then into the plateau area, will provide effective measures for the diagnosis and prevention of AMS.
出处
《医学综述》
2017年第23期4610-4615,共6页
Medical Recapitulate
