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循环肿瘤细胞的研究进展 被引量:4

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摘要 循环肿瘤细胞(CTC)是指经过自发或因临床诊疗操作由原发灶或转移灶释放然后进入外周血循环的肿瘤细胞,研究表明其是恶性肿瘤患者术后复发和发生远处转移的一个重要原因。随着检测技术的不断提高,CTC检测逐渐成为一种新颖的无创性检测手段,在早期诊断恶性肿瘤、监测复发、治疗疗效与预后评估等方面的应用在临床上越来越普遍。同时由CTC衍生出来的循环肿瘤脱氧核糖核酸(ctDNA)检测也成为了临床研究热点。本研究收集国内外有关CTC及ctDNA文献进行综述。
出处 《安徽医科大学学报》 CAS 北大核心 2017年第12期1897-1900,共4页 Acta Universitatis Medicinalis Anhui
基金 安徽医科大学第一附属医院2014后备人才项目 安徽省高等学校省级自然科学研究项目(编号:KJ2016A323)
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  • 1Paterlini - Brechot P, Benali NL. Circulating tumor cells ( CTC ) detection:clinical impact and future directions [ J ]. Cancer Lett, 2007,253 : 180 - 204.
  • 2Steeg PS. Tumor metastasis : mechaniatic insights and clinical chal- lenges [ J ]. Nat Med,2006,12 ( 8 ) : 895 - 904.
  • 3Maheswaran S, Haher DA. Circulating tumor cells: a window into cancer biology and metas- tasis[J]. Curt Opin Genet Dev,2010, 20:96 - 99.
  • 4Ashworth TR. A case of cancer in which cells similar to those in the tumors were seen in the blood after death[ J]. Aust Med J, 1896, 14:146.
  • 5Dittmar T, Heyder C, Gloria - Maercker E, et al. Adhesion mole- cules and chemokines :the nay - igation system for circulating tumor (stem) ceils to metastasize in an organ -specific manner[ J]. Clin Exp Metastasis ,2008,25 ( 1 ) : 11 - 32.
  • 6Fidler IJ. The pathogenesis of cancer metastasis: the seed and soil hypothesis revisited [ J ]. Nat Rev Cancer, 2003,3 ( 6 ) :453 - 458.
  • 7Muller V, Stahmann N, Riethdod S, et al. Circulating tumor ceils in breast cancer: correlation to bone marrow micrometastases, heteroge- neous response to systemic therapy and low pmliferative activity [ J ]. Clin Cancer Res,2005,11 (10) :3678 - 3685.
  • 8Pachmann K, Clement JH, Schneider CP, et al. Standardized quan- tification of circulating peripheral tumor cells from lung and breast cancer[ J]. Clin Chem Lab Med,2005,43:617 -627.
  • 9lalle M, de Rosa L, Marzetti L, et al. Detection of breast cancer cells in the bone marrow or peripheral blood:methods and prog- nostic significance [ J ]. Tumeri ,2000,86 (3) : 183 - 190.
  • 10Guo J, Yao F, Lou Y, et al. Detecting carcinoma cells in peripheral blood of patients with hepatocellular carcinoma by immunomagnef- ic beads and RT - PCR [ J ]. J Clin Gastroenterol,2007,41 ( 8 ) : 783 - 788.

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