摘要
目的 :分析人工关节置换术后假体周围感染细菌分布特点、耐药情况及药物治疗,为治疗假体周围感染提供参考。方法:回顾性统计60例发生髋、膝关节置换术后感染细菌培养阳性患者,对相关数据进行分析。结果:髋、膝关节置换术后假体周围感染各30例,其中G^+菌51例,G^-菌6例,真菌3例,葡萄球菌属为主要检出菌,共45例,对青霉素耐药率较高。患者根据药敏选择用药,疗效确定。结论:G^+球菌为髋、膝关节置换术后假体周围感染的主要致病菌,而凝固酶阴性葡萄球菌所占比例最高,正确选用抗菌药物,同时做好患者用药教育,保证治疗疗程,可有效提高治疗疗效。
Objective：To provide evidence for prosthetic joint infections by investigating distribution of pathogenic bacteria,drug resistant situation and drug therapy among patients with prosthetic joint infections after prosthetic joint replacement.Methods：A retrospective analysis was conducted on 60 infected patients after hip arthroplasty or knee arthroplasty and the data were analyzed.Results：There were 30 cases infected in knee arthroplasty and hip arthroplasty separately,with 51 cases infected by Gram-positive bacteria,6 by Gram-negative bacteria and 3 by fungi.The staphylococcus was the major pathogen showing high resistance to penicillin.Treatment based on drug sensitive test showed clinical efficacy.Conclusion：The Gram-positive bacteria are major pathogen in prosthetic joint infections after hip arthroplasty and knee arthroplasty,and Coagulase-negative Staphylococcus is the most common organism.Clinical efficacy is significantly improved by reasonable choice of antibiotics,effective medicine education and sufficient treatment course.
出处
《临床药物治疗杂志》
2017年第6期44-47,共4页
Clinical Medication Journal
关键词
假体周围感染
细菌
耐药
药物治疗
Prosthetic joint infection
bacteria
drug resistence
drug therapy
