摘要
目的:探讨经口内镜下肌切开术(POEM)对不同亚型贲门失弛缓症不同治疗疗效及安全性。方法:随机选取接受POEM治疗的贲门失弛缓症患者共64例为研究对象,其中芝加哥Ⅰ型组和Ⅱ型各32例,观察两组患者手术切口长度、手术持续时间、术后住院天数、手术并发症、手术前后Eckardt评分等指标,并行统计学对比分析。结果:两组患者均成功完成手术,两组在手术切口长度、术中并发症、术后并发症及术后住院天数方面相比无明显差异(P>0.05);Ⅱ型组患者手术时间明显短于Ⅰ型组患者(P<0.05),Ⅱ型组患者术后Eckardt评分平均下降程度显著高于Ⅰ型组,差异有统计学意义(P<0.05)。结论:POEM治疗贲门失弛缓症对Ⅰ型、Ⅱ型均可明显改善患者临床症状,并发症少、安全性好,但应用于Ⅱ型患者中手术时间更短、术后疗效更好。
Objective To investigate the safety and cliniacal significance of peroral endoscopic myotomy（ POEM） in the treatment of different types of achalasia. Method 64 patients with achalasia were selected as objects and they were divided into two groups according to the Eckardt scores with 32 cases in Ⅰ and 32 in Ⅱ. The length of the incision,operation time,days in hospital after operation,complications and Eckardt scores before and after operation were compared. Results All the operations were successful,surgery incision length,complications in and after operation and days in hospital after surgery of two groups had no statistical difference（ P〉0. 05）;The operation time of Ⅱ was more shorter than that in Ⅰ（ P〈0. 05）;the Eckardt scoring average loss in Ⅱ was more higher than Ⅰ（ P〈0. 05）. Conclusion POEM as a treatment of achalasia can obviously prove clinical symptoms and with less complications,high security both in type Ⅰ and Ⅱ,while patients in type Ⅱ have shorter operation time and postoperative efficacy.
出处
《吉林医学》
CAS
2017年第11期2056-2058,共3页
Jilin Medical Journal
