摘要
目的探讨血清胆红素与尿酸(UA)检验对冠心病(CHD)患者的临床诊断价值。方法 70例CHD患者设为CHD组,同期70例体检的健康人设为健康组。CHD组根据冠状动脉狭窄程度积分(Gensini)不同划分为四组,即0~1分组(18例),2~20分组(20例),21~40分组(17例)及>40分组(15例)。检测各组血清胆红素及UA水平,观察不同组别研究对象血清胆红素及UA的差异。结果 CHD组UA水平为(403.7±51.6)μmol/L,高于健康组的(268.9±34.8)μmol/L,CHD组血清总胆红素(TBIL)水平为(11.2±1.7)μmol/L、间接胆红素(IBIL)水平为(8.2±2.0)μmol/L、直接胆红素(DBIL)水平为(3.0±0.7)μmol/L,均低于健康组的(14.5±2.8)、(9.1±2.7)、(5.1±1.1)μmol/L,差异均有统计学意义(P<0.05)。21~40分组、>40分组的UA水平高于0~1分组,血清胆红素水平低于0~1分组;>40分组的UA水平高于2~20分组及21~40分组;>40分组的DBIL水平低于2~20分组;差异均有统计学意义(P<0.05)。结论检测血清胆红素与UA水平可辅助临床诊断CHD患者并评估其冠状动脉狭窄的程度,有利于临床治疗与评估预后,值得推广。
Objective To investigate the clinical diagnostic value of serum bilirubin and uric acid（UA） detection in patients with coronary heart disease（CHD）.Methods There were 70 CHD patients as CHD group,and concurrent 70 healthy people for physical examination as healthy group.CHD group were divided by different coronary narrow degree integral（Gensini） into four groups,including 0~1 point group（18 cases）,2~20 points group（20 cases）,21~40 points group（17 cases） and 〉40 points group（15 cases）.Detection were made on serum bilirubin and UA levels,and observation were made on differences of serum bilirubin and UA in different groups.Results CHD group had higher UA levels as（403.7±51.6） μmol/L than（268.9±34.8） μmol/L in healthy group.CHD group had serum total bilirubin（TBIL） level as（11.2±1.7） μmol/L,indirect bilirubin（IBIL） level as（8.2±2.0） μmol/L,direct bilirubin（DBIL） levels as（3.0±0.7） μmol/L,which were all lower than（14.5±2.8）,（9.1±2.7） and（5.1±1.1） μmol/L in healthy group.Their difference was statistically significant（P〈0.05）.21~40 points group and 〉40 points group had higher UA level than 0~1 point group,lower serum bilirubin level than 0~1 point group.〉40 points group had higher UA levels than 2~20 points group and 21~40 points group.〉40 points group had lower DBIL level than 2~20 points group.Their difference was statistically significant（P〈0.05）.Conclusion The detection of serum bilirubin and UA levels can assist the clinical diagnosis of CHD patients and assess the severity of coronary stenosis,and it is beneficial to the clinical treatment and evaluation of prognosis.So it is worthy of promotion.
作者
萧飞
XIAO Fei.(Department of Clinical Laboratory, Maoming City People＇s Hospital, Maoming 525000, Chin)
出处
《中国实用医药》
2017年第29期33-35,共3页
China Practical Medicine
关键词
冠心病
血清胆红素
尿酸
Coronary heart disease
Serum bilirubin
Uric acid
