摘要
为了提高实验的教学质量,减少环境污染,对磺胺醋酰钠的合成方法进行改进。以药用磺胺为原料,醋酐为酰化剂,在碱性溶液中制备磺胺醋酰钠。以苄基三乙基氯化铵为催化剂时,磺胺醋酰钠的收率为56.1%。
The synthesis method of sulfacetamide sodium was carried to improve the teaching quality,reduce environmental pollution. The experiment was carried under alkaline condition with medicinal sulfadiazine as raw material,acetic anhydride as acylating agent in alkaline solution. The yield of sulfacetamide sodium was 56. 1 % when benzyl triethyl ammonium chloride was used as catalyst.
出处
《山东化工》
CAS
2017年第18期166-167,共2页
Shandong Chemical Industry
基金
浙江省2015年度高等教育课堂教学改革项目(kg2015624)
浙江省2015年度高等教育教学改革项目(jg2015258)
关键词
磺胺醋酰钠
合成
催化
sulfacetamide sodium
synthesis
catalysis
