摘要
目的:综合分析不同剂量吡嗪酰胺治疗肺结核的临床效果,为治疗肺结核患者提供科学的数据参考。方法:选取在本院(2014年12月—2016年12月)收治的120例肺结核患者,按照入院顺序随机分为A组(应用1.5g/d吡嗪酰胺治疗,40例)、B组(应用0.75g/d吡嗪酰胺治疗,40例)、C组(应用0.5g/d吡嗪酰胺治疗,40例)。采用SPSS20.0统计学软件进行统计学分析三组患者的临床治疗总有效率、不良反应发生率(连续治疗一个疗程后出现不良反应)。结果:(1)C组临床治疗总有效率显著高于A组、B组,数据比较差异有统计学意义(P<0.05);(2)C组不良反应发生率显著低于B组、A组,数据比较差异有统计学意义(P<0.05)。结论:应用1.5g/d吡嗪酰胺治疗方法治疗肺结核患者的临床效果最佳。
Objective To comprehensively analyze the clinical effect of different doses of pyrazinamide on tuberculosis and provide scienti？c data reference for treating pulmonary tuberculosis patients. Methods： 120 cases of pulmonary tuberculosis patients in our college （December 2014 - December 2016） were randomly divided into group A （1.5 g/d pyrazinamide treatment method, 40 cases） and group B （0.75 g/d pyrazinamide treatment method, 40 cases） and group C （0.5 g/d pyrazinamide treatment method, 40 cases）. SPSS20.0 statistical software was used to analyze the clinical treatment of three groups of patients with total effective and adverse reaction rate （adverse reactions after a course of treatment）. Results： The total effective rate of clinical treatment in group C was signi？cantly lower than that in group A and group B, and the difference in data was statistically signi？cant （P〈0.05）. The incidence of adverse reactions in group C was signi？cantly lower than that in group B and group A （P〈0.05）. Conclusion： 1. 1.5 g/d pyrazinamide is used to treat pulmonary tuberculosis patients with the best clinical effect.
出处
《药品评价》
CAS
2017年第20期30-31,34,共3页
Drug Evaluation
关键词
不同剂量
吡嗪酰胺
肺结核
临床效果
Different Dosage
Pyrazinamide
Tuberculosis
Clinical Effect
