摘要
前列腺癌(prostate cancer,PCa),在欧美是很严重的人类疾病,中国及亚洲PCa发生率增长较快。了解PCa发生发展的流行病学,对于PCa的筛查预防及诊治有重要意义。一般将PCa的危险因素分为不可改变因素与可改变因素。在可改变因素中,对PCa影响较大的有茄红素、硒的摄入,药物中包括5α还原酶抑制剂、他汀类和二甲双胍等,输精管结扎术对PCa的影响也有新观点。本文将新近大样本、有代表性的研究成果进行了综述。
Prostate cancer（PCa）is a very serious human disease in Europe and America,and the incidence of PCa is growing rapidly in China and Asia.Understanding the epidemiology of PCa development is of great significance for the prevention and treatment of PCa.Generally,the risk factors of PCa can be divided into non-changing factors and changing factors.Among the factors that could be changed,the influence of lycopene and selenium on PCa was higher.Also,the influence of some medicines was high including 5-alpha reductase inhibitors,statins and metformin and so on.The influence of vasectomy on PCa also has new perspectives.In this paper,a large sample and representative research results are reviewed.
作者
杨进益
杨明州
魏伟
岳文昌
YANG Jinyi YANG Mingzhou WEI Wei YUE Wenchang(Department of Urology, Dalian Friendship Hospital of Dalian Medical University, Dalian, Lia- oning, 116001, China)
出处
《临床泌尿外科杂志》
2017年第9期721-725,共5页
Journal of Clinical Urology
关键词
前列腺癌
流行病学
prostate cancer
epidemiology
