摘要
单氟烯烃在新材料开发和新药研发等多个领域具有广泛的用途,其高立体选择性合成受到高度关注.本综述主要介绍了基于醛、酮、重氮化合物以及其他底物如炔烃、烯基金属物种以及烯烃的高立体选择性合成单氟烯烃的研究进展,并藉此讨论不同方法的一些优势和不足之处.
Monofluoroalkenes have found applications in many areas of research, including the design and development new materials and drug. The highly stereoselective synthesis of this privileged structural motif has attracted great synthetic attention. This review summarizes recent progresses in highly stereoselective synthesis of monofluoroalkenes from aldehydes, ketones and diazo compounds, other substrates such as alkynes, alkenyl metallic species and alkenes are also included. The advantages and disadvantages of different methods are discussed.
作者
廖富民
余金生
周剑
Liao Fumin Yu Jinsheng Zhou Jian(Shanghai Key Laboratory, of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal Univerity, Shanghai 200062 State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2017年第9期2175-2186,共12页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21472049)资助项目~~
关键词
单氟烯烃
立体选择性合成
醛和酮
重氮化合物
monofluoroalkene
stereoselective synthesis
aldehyde and ketone
diazo compound
