摘要
本文利用一阶导数高速脉冲极谱法定量分析醋酸泼尼松及其制剂。在1.2×10~2mol/LH_2SO_4的乙醇和水(3:2)的底液中,于-1.05 V(vs Ag/AgCl)处出现一良好的峰,在5.0×10~5～2.5×10^(-4)mol/L范围内,药物浓度与峰电流呈线性关系。检测限为2.5×10^(-10)mol/L。本法操作简便、快速、灵敏,结果准确。
The first derivative high-speed pulse polarography was developed for the determination of the prednisone acetate and its preparation. By using ethanol-water solution containing 1.2×10^(-2) mol/L sulfuric acid, there was a very good peak at — 1.05 V (vs Ag/AgCl). The linear relarionship between concentration and peak current was obtained in the concentration range of 5.0×10^(-5)～2.5×10^(-4) mol/L. The determination limit is 2.5×10^(-10) mol/L. This method is simple, rapid and sensitive. The result is accurate.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1991年第2期77-79,共3页
Journal of China Pharmaceutical University
关键词
醋酸泼尼松
定量分析
高速脉冲极谱
First derivative high-speed pulse polarography
Prednisone acetate
Prednisone acetate tablets
