摘要
目的探讨帕金森病(PD)丘脑底核(STN)脑深部电刺激(DBS)术中电极位置的监测和校准。方法对20例帕金森病患者进行双侧STN DBS治疗,植入40侧电极,通过术中微电极记录(MER)和X线成像进行电极位置的监测和校准。结果所有患者的术后程控效果良好,术后1年,患者的UPDRSⅢ总分在开机未服药状态下明显下降(P<0.05)。结论通过MER和X线成像可以监测到靶点的偏差和电极的移位并实时纠正,提高手术疗效,减少手术并发症。
Objective To explore the monitoring and revision of electrode in STN DBS surgery for Parkinson＇s disease （PD） patients. Methods A total of 20 cases of PD patients were input 40 electrodes in bilateral STN DBS surgery. Intraoperative microelectrode recording （MER） and X-ray imaging were used to monitor and revise the location of electrodes. Results All patients had good postoperative program control efficacy. 1 year after surgery, the total score of UPDRS 1I in the state of power-on and medication-offdecreased significantly （P〈0.05）. Conclusions The application of MER and X-ray imaging can monitor the deviation of target and the shift of electrode, and correct the dislocation in real time, so as to improve surgical efficacy and reduce surgical complications.
出处
《临床医学工程》
2017年第10期1333-1334,共2页
Clinical Medicine & Engineering
基金
广东省科技计划项目(项目编号:2013B090500098)
关键词
帕金森病
脑深部电刺激
丘脑底核
微电极记录
X线成像
Parkinson＇s disease
Deep brain stimulation
Subthalamic nucleus
Microelectrode recording
X-ray imaging
