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恶性胶质瘤术后放化疗效果及影响因素分析 被引量:2

Efficacy and influencing factors of postoperative radiotherapy and chemotherapy for malignant glioma
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摘要 目的分析恶性胶质瘤术后放、化疗的效果与影响因素。方法以我院收治的60例恶性胶质瘤患者为研究对象,所有患者接受手术治疗,并于术后进行放、化疗,分析影响放疗与化疗效果的各项因素。结果 7例完全缓解,36例部分缓解,总缓解率为71.67%(43/60);随访发现复发23例(38.33%),死亡27例(45.00%),存活33例(55.00%)。结论恶性胶质瘤手术疗效受术前癫痫发作、肿瘤病理分级、肿瘤全切因素影响,于术后采用放疗结合替莫唑胺进行化疗,效果良好,值得临床推广。 Objective To analyze the effect and influencing factors of postoperative radiotherapy and chemotherapy in ma- lignant glioma. Methods Sixty patients with malignant glioma in our hospital were enrolled as the research subjects. All patients underwent surgical treatment following by radiotherapy and,chemotherapy,and the influencing factors of radiotherapy and chemo- therapy effects were analyzed. Results Seven cases were completely relieved, the total remission rate was 71.67 % (43/60). Follow-up found the glioma relapsed in 23 cases (38.33%). 27 cases died(45.00%) and 33 cases survived (55.00%). Conclusion The effect of malignant glioma surgery is influnced by preoperative seizures, tumor pathological grade and tumor total cut rate. Radiotherapy combined with temozolomide for chemotherapy has a good effect and is worthy of clinical promotion.
作者 郭小奇 单娟
出处 《中国实用神经疾病杂志》 2017年第16期30-33,共4页 Chinese Journal of Practical Nervous Diseases
关键词 恶性胶质瘤 放疗 化疗 Malignant glioma Radiotherapy Chemotherapy
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