摘要
为研究人参茎叶提取物对Ⅰ型糖尿病的影响,选取40只清洁级雄性昆明小鼠以剂量120 mg/kg·体重腹腔注射链脲佐菌素(STZ)建立Ⅰ型糖尿病小鼠模型,试验期间定时检测小鼠体重及空腹血糖值,试验20d后眼球取血处理得血清,测定小鼠血清总胆固醇(TC)、甘油三酯(TG)、超氧化物歧化酶(SOD)及丙二醛(MDA)含量并进行分析。结果显示,一定剂量的人参茎叶提取物悬浊液有助于改善Ⅰ型糖尿病小鼠的抗氧化能力,降低血清血脂水平,对缓解糖尿病并发症有重要意义。
In order to study the function effects of Panax ginseng stems and leaves extract on type Ⅰ diabetic,40 male CL grade Kunming mice were injected with STZ at 120mg/kg body weight to induce type Ⅰ diabetes mice model,and body weight and blood glucose were measured during the experiment.After 20days' test,blood serum was obtained by eye's blood of mice and the total cholesterol(TC),triglyceride(TG),superoxide dismutase(SOD)and malondialdehyde(MDA)were all measured by kits.The results showed that the extract of ginseng stems and leaves at a certain dose can improve the antioxidant capacity of type Ⅰ diabetic mice and reduce the serum lipid which to alleviates the complications of diabetes mellitus.
出处
《食品与机械》
CSCD
北大核心
2017年第7期165-169,共5页
Food and Machinery
基金
辐照保藏四川省重点实验室开放课题项目(编号:SCFZBC2017003)
关键词
人参
糖尿病
血清
总胆固醇
甘油三酯
Ginseng stem and leaf extract
diabetes
serum
total cholesterol
triglyceride