摘要
目的评价心肌灌注显像后处理时采用FBP与不同迭代次数和子集数的OSEM重建法所得心功能指标结果是否存在差异,并推荐适于临床的处理参数。方法回顾性分析2012年1月到2014年12月间行心肌灌注显像的66例患者资料,其中男33例,女33例,年龄18~77岁。使用FBP及OSEM(4~16个子集数以及2~4次迭代次数,共5种方法)重建后,通过QGS分析心功能参数(EDV、ESV、LVEF)是否存在差异,并将所得结果与心脏超声结果进行比对。采用单因素方差分析分析数据。结果方差分析结果示,6种重建方法所得的LVEF[(66.14±11.12)%、(75.05±12.10)%、(70.09±11.27)%、(66.88±10.38)%、(64.97±10.25)%和(62.58±9.84)%]、EDV[(77.32±27.58)、(67.97±27.56)、(75.10±27.89)、(81.03±28.11)、(84.94±29.07)和(89.98±29.71) ml]和ESV[(28.71±10.04)、(19.71±16.51)、(25.13±17.66)、(29.01±18.47)、(32.10±19.63)和(35.83±20.41) ml]差异有统计学意义(F值:10.73、4.89和5.97;均P〈0.05)。OSEM(2次迭代、12个子集)与心脏超声结果最为接近。结论6种心肌灌注显像图像后处理方式中,OSEM中2次迭代、12个子集重建方法较适合临床应用。
Objective To evaluate the influences of FBP and OSEM ( with different iteration numbers or subset numbers) on cardiac function parameters with MPI, and to identify a suitable clinical method. Methods The MPI of 66 patients (33 males, 33 females, age range: 18-77 years) from January 2012 to December 2014 were retrospectively analyzed. The imaging data was reconstructed with FBP and 5 different OSEM (4-16 subsets and 2-4 iterations) in order to evaluate if there was any difference of cardiac function parameters calculated by QGS between the different image processing methods. In addition, the results were compared with those of cardiac uhrasonography. One-way analysis of variance was used for data analysis. Results The statistical differences of LVEF, EDV, and ESV (F values: 10.73, 4.89 and 5.97, all P〈 0. 05) were found among 6 reconstructed methods. The values of LVEF were (66.14±11.12)%, (75.05± 12.10)%, (70.09±11.27)%, (66.88±10.38)%, (64.97-10.25)%, and (62.58±9.84)%. Those of EDV were (77.32±27.58), (67.97±27.56), (75.10±27.89), (81.03±28.11), (84.94±29.07), and (89.98±29.71) ml, and the ESV values were (28.71±10.04), (19.71±16.51), (25.13±17.66), (29.01± 18.47) , ( 32.10± 19.63) , and ( 35.83 ±20.41 ) ml respectively. The cardiac function parameters measured by OSEM (with 2 iterations, 12 subsets) were much similar to that measured by cardiac uhrasonography. Conclusion Compared with other 5 processing methods of MPI, the OSEM (with 2 iterations, 12 subsets) method may be more suitable for practical clinical application.
出处
《中华核医学与分子影像杂志》
北大核心
2017年第9期564-567,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging