摘要
目的探讨单采血小板联合新鲜冰冻血浆治疗急性肝脾破裂大出血的临床效果。方法选择2016年2月—2017年2月重庆三峡中心医院收治的急性腹部闭合性损伤患者80例,按照随机数字法分为两组,各40例,对照组在及时补充去白红细胞同时,及时输注新鲜冰冻血浆,观察组则及时测定患者血小板计数,比较干预后两组凝血功能检测结果,干预前后两组血小板水平变化情况,并统计两组止血时间及临床救治成功率。结果干预后观察组凝血功能检查指标中PT(13.5±1.1)s、TT(11.5±2.4)、APTT(21.6±1.3)s及Fib(1.7±0.3)g/L等均显著优于对照组(t=49.862、18.250、18.000、34.924,P<0.05),干预后观察组血小板水平为(114.3±14.3)×109/L,显著高于干预前(t=43.011,P<0.05),干预后对照组血小板水平为(39.3±1.1)×109/L,显著低于干预前(t=16.323,P<0.05),观察组止血时间为(39.3±3.4)min,显著短于对照组(t=17.606,P<0.05),救治成功率达到97.5%,显著高于对照组(χ2=6.746,P<0.05)。结论针对急性失血性休克患者,观察组使用血小板联合新鲜冰冻血浆治疗,能有效改善患者凝血功能,提高血小板水平,缩短止血时间,提高救治成功率。
Objective This paper tries to investigate the clinical effect of single platelet combined with fresh frozen plasma for acute liver and spleen rupture hemorrhage. Methods 80 cases with acute abdominal closed injury admitted in this hospital from February 2016 to February 2017 were randomly divided into two groups according to the random number method,with 40 cases in each group. The control group was supplemented with white blood cells and fresh frozen plasma,the observation group was measured with platelet count ,then coagulation test results,platelet levels changes,bleeding time and clinical success rate of the two groups before and after were compared. Results After in te r -vention, coagulation function test indicators with PT in the observation group was （13.5±1.1） s,TT was （11.5±2.4）s, APTT was （21.6±1.3）s and Fib was （1.7±0.3）g/L,significantly better than those in the control group （t=49.862, 18.250, 18.000, 34.924,P〈0.05）; the level of platelet in the observation group was （114.3±14.3）× 10^ 9/L,significantly higher than that before the intervention （t = 43 .011 ,P 〈0.05）. The platelet level in the control group was （39.3±1.1） ×10^9/L, which was significantly higher than that before the intervention （t=16.323, P〈0.05）. The time of hemostasis in the ob-servation group was （39.3 ± 3.4） min, which was significantly shorter th an that in the control group （ t=17.606, P 〈 0 .0 5）, the success rate in the observation group was 97.5%,which was significantly higher than that of the control group （x^2=6.746, P〈0.05）. Conclusion For patients with acute hemorrhagic shock, the platelet combined with fresh frozen plasma therapy in the observation group could effectively improve the coagulation function and improve platelet levels, which can shorten the hemostasis time and improve the success rate.
出处
《系统医学》
2017年第13期24-26,30,共4页
Systems Medicine
关键词
单采血小板
新鮮冰冻血浆
急性肝脾破裂
大出血
Single platelets
Fresh frozen plasma
Acute liver and spleen rupture
Hemorrhage
