摘要
OSAHS是一种很常见的睡眠呼吸紊乱疾病,影响着多达9%的男性和4%的女性（[1]）。OSAHS患者睡眠过程中主要的解剖现象是上气道塌陷,最常见的症状是嗜睡和神经认知功能障碍,心脑血管疾病是其最严重的并发症,近年来发病率在不断提高。OSAHS及其并发症具有长期性、隐蔽性和猝发性的特点,可对健康造成潜在的重大威胁.
Summary OSAHS is a common disease during sleep and its pathogenesis is complex. The anatomic level of upper airway is a more recognized pathogenic factor. Recent studies have shown that nonanatomic factors, such as insufficiency in dilation muscles of upper airway, high loop gain and low arousal threshold, play an important role in the pathogenesis of OSAHS. This paper revives the latest literature home and abroad on the anatomical and nonan- atomical factors in the pathogenesis of OSAHS and makes a systemic review.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2017年第17期1376-1380,共5页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
解剖因素
上气道扩张肌
环路增益
觉醒阈
睡眠呼吸暂停低通气综合征
阻塞性
anatomical factor
dilation muscles of upper airway
loop gain
arousal threshold
sleep apnea hy-popnea syndrome, obstructive
