摘要
建立清咽颗粒质量控制方法。采用薄层色谱法对制剂中山豆根、射干、重楼进行定性鉴别;采用高效液相色谱法对制剂中的君药山豆根中的苦参碱进行含量测定。薄层色谱可鉴别出山豆根、重楼、射干的特征斑点,阴性对照无干扰;苦参碱在10 g/mL^140 g/mL范围内呈线性关系(r=0.9998,n=7),平均回收率为99.97%(RSD1.25%)。本方法操作简便,结果准确、可靠,可用于清咽颗粒的质量控制。
To establish the standard for quality control ofQingyan Granule.The chiefcomponents ofthe preparation, Sophora Tonkinensis, paris, black berrylily were identified by TLC qualitatively.The contents of matrine were determined by HPLC.The spots in TLC were clear. There were spots with same color on the corresponding location of reference substance and reference herbal, negative control with-out interference. The linear range for matrine was 10μg/mL-140[jg/mL（ r=0.9998, n=7）. The average recovery was 99.97%（RSD=1.25%）. The method is simple, accurate, with high reproducibility, which can be used for quality control of Qingyan Granule.
出处
《特产研究》
2017年第3期17-20,共4页
Special Wild Economic Animal and Plant Research
