摘要
目的 探讨改良宫颈锥切术对宫颈上皮内瘤变（CIN）Ⅲ级患者术中出血量及术后并发症发生率的影响.方法 选取在我院接受治疗的CIN Ⅲ级患者88 例,按照手术术式分组,冷刀宫颈锥切组44 例,改良宫颈锥切组44 例.比较两组手术情况、术后复查情况及并发症发生率,并检测对比两组术后免疫球蛋白G（IgG）、IgM、IgA 水平变化情况.结果 改良宫颈锥切组手术时间及术中出血量较冷刀宫颈锥切组少,差异有统计学意义（P 〈 0.05）;术后改良宫颈锥切组IgM、IgG、IgA 水平较冷刀宫颈锥切组高,差异有统计学意义,（P 〈 0.05）;改良宫颈锥切组术后发热及术后出血发生率低于冷刀宫颈锥切组,差异有统计学意义（P 〈 0.05）;改良宫颈锥切组治愈率（90.91%）较冷刀宫颈锥切组（50.00%）高,持续存在及复发率低于冷刀宫颈锥切组,差异有统计学意义（P 〈 0. 05）.结论 采用改良宫颈锥切术治疗宫颈上皮内瘤变Ⅲ级,可降低术中出血量,改善患者预后.
Objective To i nvestigate t he effect of modified c ervical c onization on t he i ntraoperative blood loss a nd t heincidence of postoperative complications in cervical intraepithelial neoplasia （CIN） III grade. Methods Selected 88 patientswith CIN III grade in our hospital were divided into cold knife cervical conization group （n=44） and modified cervicalconization （n=44） according to surgery. Surgery, postoperative review and the incidence of complications were comparedbetween the two groups, and the immunoglobulin G （IgG）, IgM and IgA levels change were examined and comparedafter operation. Results T he o perative t ime a nd i ntraoperative blood loss i n t he modified c ervical c onization g roup weresignificantly lower than those in the cold knife cervical conization group （P 〈0.05）; The IgM, IgG and IgA levels in themodified cervical conization group were significantly higher than those in the cold knife cervical conization group （P 〈0.05）;The postoperative fever and the incidence of postoperative bleeding in the modified cervical conization group were lowerthan thatin the cold knife cervical conization group , the difference was statistically significant （P 〈0.05）; The persistenceand recurrence rates were lower than those in the observation group, and the difference was statistically significant （P 〈0.05）.Conclusion The modified cervical conization in the treatment of cervical intraepithelial neoplasia grade III can reduce theintraoperative blood loss and improve the prognosis of the patients.
出处
《临床研究》
2017年第8期35-36,共2页
Clinical Research
关键词
宫颈锥切术
宫颈上皮内瘤变
出血量
并发症
cervical conization
cervical intraepithelial neoplasia
bleeding volume
complications
